Autosomal-dominant B-cell deficiency with alopecia due to a mutation in NFKB2 that results in nonprocessable p100

Por Lee, Cindy Eunhee, Fulcher, David A., Whittle, Belinda, Chand, Rochna, Fewings, Nicole, Field, Matthew, Andrews, Daniel, Goodnow, Christopher C., Cook, Matthew C.
Publicado no Blood (2014)

Deficiency of Th17 cells in hyper IgE syndrome due to mutations in STAT3

Por Ma, Cindy S., Chew, Gary Y.J., Simpson, Nicholas, Priyadarshi, Archana, Wong, Melanie, Grimbacher, Bodo, Fulcher, David A., Tangye, Stuart G., Cook, Matthew C.
Publicado em 2008

IL-27 supports germinal center function by enhancing IL-21 production and the function of T follicular helper cells

Por Batten, Marcel, Ramamoorthi, Nandhini, Kljavin, Noelyn M., Ma, Cindy S., Cox, Jennifer H., Dengler, Hart S., Danilenko, Dimitry M., Caplazi, Patrick, Wong, Melanie, Fulcher, David A., Cook, Matthew C., King, Cecile, Tangye, Stuart G., de Sauvage, Frederic J., Ghilardi, Nico
Publicado em 2010

IL-21 signalling via STAT3 primes human naïve B cells to respond to IL-2 to enhance their differentiation into plasmablasts

Por Berglund, Lucinda J., Avery, Danielle T., Ma, Cindy S., Moens, Leen, Deenick, Elissa K., Bustamante, Jacinta, Boisson-Dupuis, Stephanie, Wong, Melanie, Adelstein, Stephen, Arkwright, Peter D., Bacchetta, Rosa, Bezrodnik, Liliana, Dadi, Harjit, Roifman, Chaim M., Fulcher, David A., Ziegler, John B., Smart, Joanne M., Kobayashi, Masao, Picard, Capucine, Durandy, Anne, Cook, Matthew C., Casanova, Jean-Laurent, Uzel, Gulbu, Tangye, Stuart G.
Publicado em 2013

Functional STAT3 deficiency compromises the generation of human T follicular helper cells

Por Ma, Cindy S., Avery, Danielle T., Chan, Anna, Batten, Marcel, Bustamante, Jacinta, Boisson-Dupuis, Stephanie, Arkwright, Peter D., Kreins, Alexandra Y., Averbuch, Diana, Engelhard, Dan, Magdorf, Klaus, Kilic, Sara S., Minegishi, Yoshiyuki, Nonoyama, Shigeaki, French, Martyn A., Choo, Sharon, Smart, Joanne M., Peake, Jane, Wong, Melanie, Gray, Paul, Cook, Matthew C., Fulcher, David A., Casanova, Jean-Laurent, Deenick, Elissa K., Tangye, Stuart G.
Publicado em 2012

STAT3 mutations underlying autosomal dominant hyper-IgE syndrome impair human CD8(+) T cell memory formation and function

Por Ives, Megan L, Ma, Cindy S, Palendira, Umaimainthan, Chan, Anna, Bustamante, Jacinta, Boisson-Dupuis, Stephanie, Arkwright, Peter D, Engelhard, Dan, Averbuch, Diana, Magdorf, Klaus, Roesler, Joachim, Peake, Jane, Wong, Melanie, Adelstein, Stephen, Choo, Sharon, Smart, Joanne M, French, Martyn A, Fulcher, David A, Cook, Matthew C, Picard, Capucine, Durandy, Anne, Tsumura, Miyuki, Kobayashi, Masao, Uzel, Gulbu, Casanova, Jean-Laurent, Tangye, Stuart G, Deenick, Elissa K
Publicado em 2013

STAT3 is a critical cell-intrinsic regulator of human unconventional T cell numbers and function

Por Wilson, Robert P., Ives, Megan L., Rao, Geetha, Lau, Anthony, Payne, Kathryn, Kobayashi, Masao, Arkwright, Peter D., Peake, Jane, Wong, Melanie, Adelstein, Stephen, Smart, Joanne M., French, Martyn A., Fulcher, David A., Picard, Capucine, Bustamante, Jacinta, Boisson-Dupuis, Stephanie, Gray, Paul, Stepensky, Polina, Warnatz, Klaus, Freeman, Alexandra F., Rossjohn, Jamie, McCluskey, James, Holland, Steven M., Casanova, Jean-Laurent, Uzel, Gulbu, Ma, Cindy S., Tangye, Stuart G., Deenick, Elissa K.
Publicado no J Exp Med (2015)

B cell–intrinsic signaling through IL-21 receptor and STAT3 is required for establishing long-lived antibody responses in humans

Por Avery, Danielle T., Deenick, Elissa K., Ma, Cindy S., Suryani, Santi, Simpson, Nicholas, Chew, Gary Y., Chan, Tyani D., Palendira, Umamainthan, Bustamante, Jacinta, Boisson-Dupuis, Stéphanie, Choo, Sharon, Bleasel, Karl E., Peake, Jane, King, Cecile, French, Martyn A., Engelhard, Dan, Al-Hajjar, Sami, Al-Muhsen, Saleh, Magdorf, Klaus, Roesler, Joachim, Arkwright, Peter D., Hissaria, Pravin, Riminton, D. Sean, Wong, Melanie, Brink, Robert, Fulcher, David A., Casanova, Jean-Laurent, Cook, Matthew C., Tangye, Stuart G.
Publicado em 2010

Naive and memory human B cells have distinct requirements for STAT3 activation to differentiate into antibody-secreting plasma cells

Por Deenick, Elissa K., Avery, Danielle T., Chan, Anna, Berglund, Lucinda J., Ives, Megan L., Moens, Leen, Stoddard, Jennifer L., Bustamante, Jacinta, Boisson-Dupuis, Stephanie, Tsumura, Miyuki, Kobayashi, Masao, Arkwright, Peter D., Averbuch, Diana, Engelhard, Dan, Roesler, Joachim, Peake, Jane, Wong, Melanie, Adelstein, Stephen, Choo, Sharon, Smart, Joanne M., French, Martyn A., Fulcher, David A., Cook, Matthew C., Picard, Capucine, Durandy, Anne, Klein, Christoph, Holland, Steven M., Uzel, Gulbu, Casanova, Jean-Laurent, Ma, Cindy S., Tangye, Stuart G.
Publicado em 2013

Unique and shared signaling pathways cooperate to regulate the differentiation of human CD4(+) T cells into distinct effector subsets

Por Ma, Cindy S., Wong, Natalie, Rao, Geetha, Nguyen, Akira, Avery, Danielle T., Payne, Kathryn, Torpy, James, O’Young, Patrick, Deenick, Elissa, Bustamante, Jacinta, Puel, Anne, Okada, Satoshi, Kobayashi, Masao, Martinez-Barricarte, Ruben, Elliott, Michael, Sebnem Kilic, Sara, El Baghdadi, Jamila, Minegishi, Yoshiyuki, Bousfiha, Aziz, Robertson, Nic, Hambleton, Sophie, Arkwright, Peter D., French, Martyn, Blincoe, Annaliesse K., Hsu, Peter, Campbell, Dianne E., Stormon, Michael O., Wong, Melanie, Adelstein, Stephen, Fulcher, David A., Cook, Matthew C., Stepensky, Polina, Boztug, Kaan, Beier, Rita, Ikincioğullari, Aydan, Ziegler, John B., Gray, Paul, Picard, Capucine, Boisson-Dupuis, Stéphanie, Phan, Tri Giang, Grimbacher, Bodo, Warnatz, Klaus, Holland, Steven M., Uzel, Gulbu, Casanova, Jean-Laurent, Tangye, Stuart G.
Publicado no J Exp Med (2016)

Monogenic mutations differentially impact the quantity and quality of T follicular helper cells in human primary immunodeficiencies

Por Ma, Cindy S, Wong, Natalie, Rao, Geetha, Avery, Danielle T, Torpy, James, Hambridge, Thomas, Bustamante, Jacinta, Okada, Satoshi, Stoddard, Jennifer L, Deenick, Elissa K, Pelham, Simon J, Payne, Katherine, Boisson-Dupuis, Stéphanie, Puel, Anne, Kobayashi, Masao, Arkwright, Peter D, Kilic, Sara Sebnem, Baghdadi, Jamila El, Nonoyama, Shigeaki, Minegishi, Yoshiyuki, Mahdaviani, Seyed Alireza, Mansouri, Davood, Bousfiha, Aziz, Blincoe, Annaliesse K, French, Martyn A, Hsu, Peter, Campbell, Dianne E., Stormon, Michael O, Wong, Melanie, Adelstein, Stephen, Smart, Joanne M, Fulcher, David A, Cook, Matthew C, Phan, Tri G, Stepensky, Polina, Boztug, Kaan, Kansu, Aydan, Ikincioğullari, Aydan, Baumann, Ulrich, Beier, Rita, Roscioli, Tony, Ziegler, John B, Gray, Paul, Picard, Capucine, Grimbacher, Bodo, Warnatz, Klaus, Holland, Steven M, Casanova, Jean-Laurent, Uzel, Gulbu, Tangye, Stuart G
Publicado no J Allergy Clin Immunol (2015)