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STAT3 is a critical cell-intrinsic regulator of human unconventional T cell numbers and function

Unconventional T cells such as γδ T cells, natural killer T cells (NKT cells) and mucosal-associated invariant T cells (MAIT cells) are a major component of the immune system; however, the cytokine signaling pathways that control their development and function in humans are unknown. Primary immunode...

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Publicat a:J Exp Med
Autors principals: Wilson, Robert P., Ives, Megan L., Rao, Geetha, Lau, Anthony, Payne, Kathryn, Kobayashi, Masao, Arkwright, Peter D., Peake, Jane, Wong, Melanie, Adelstein, Stephen, Smart, Joanne M., French, Martyn A., Fulcher, David A., Picard, Capucine, Bustamante, Jacinta, Boisson-Dupuis, Stephanie, Gray, Paul, Stepensky, Polina, Warnatz, Klaus, Freeman, Alexandra F., Rossjohn, Jamie, McCluskey, James, Holland, Steven M., Casanova, Jean-Laurent, Uzel, Gulbu, Ma, Cindy S., Tangye, Stuart G., Deenick, Elissa K.
Format: Artigo
Idioma:Inglês
Publicat: The Rockefeller University Press 2015
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4451129/
https://ncbi.nlm.nih.gov/pubmed/25941256
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20141992
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