STAT3 mutations underlying autosomal dominant hyper-IgE syndrome impair human CD8(+) T cell memory formation and function

BACKGROUND: The capacity of CD8(+) T cells to control infections and mediate anti-tumor immunity requires the development and survival of effector and memory cells. IL-21 has emerged as a potent inducer of CD8(+) T cell effector function and memory development in mouse models of infectious disease....

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: Ives, Megan L, Ma, Cindy S, Palendira, Umaimainthan, Chan, Anna, Bustamante, Jacinta, Boisson-Dupuis, Stephanie, Arkwright, Peter D, Engelhard, Dan, Averbuch, Diana, Magdorf, Klaus, Roesler, Joachim, Peake, Jane, Wong, Melanie, Adelstein, Stephen, Choo, Sharon, Smart, Joanne M, French, Martyn A, Fulcher, David A, Cook, Matthew C, Picard, Capucine, Durandy, Anne, Tsumura, Miyuki, Kobayashi, Masao, Uzel, Gulbu, Casanova, Jean-Laurent, Tangye, Stuart G, Deenick, Elissa K
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: 2013
विषय:
Article
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC3785237/
https://ncbi.nlm.nih.gov/pubmed/23830147
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jaci.2013.05.029
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