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Naive and memory human B cells have distinct requirements for STAT3 activation to differentiate into antibody-secreting plasma cells
Long-lived antibody memory is mediated by the combined effects of long-lived plasma cells (PCs) and memory B cells generated in response to T cell–dependent antigens (Ags). IL-10 and IL-21 can activate multiple signaling pathways, including STAT1, STAT3, and STAT5; ERK; PI3K/Akt, and potently promot...
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| Auteurs principaux: | , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
The Rockefeller University Press
2013
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3832925/ https://ncbi.nlm.nih.gov/pubmed/24218138 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20130323 |
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