Deficiency of Th17 cells in hyper IgE syndrome due to mutations in STAT3

Hyper–immunoglobulin E syndrome (HIES) is a primary immune deficiency characterized by abnormal and devastating susceptibility to a narrow spectrum of infections, most commonly Staphylococcus aureus and Candida albicans. Recent investigations have identified mutations in STAT3 in the majority of HIE...

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Bibliografiske detaljer
Main Authors: Ma, Cindy S., Chew, Gary Y.J., Simpson, Nicholas, Priyadarshi, Archana, Wong, Melanie, Grimbacher, Bodo, Fulcher, David A., Tangye, Stuart G., Cook, Matthew C.
Format: Artigo
Sprog:Inglês
Udgivet: The Rockefeller University Press 2008
Fag:
Brief Definitive Reports
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2442632/
https://ncbi.nlm.nih.gov/pubmed/18591410
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20080218
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