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B cells require DOCK8 to elicit and integrate T cell help when antigen is limiting
Dedicator of cytokinesis 8 (DOCK8) immunodeficiency syndrome is characterized by a failure of the germinal center response, a process involving the proliferation and positive selection of antigen-specific B cells. Here, we describe how DOCK8-deficient B cells are blocked at a light-zone checkpoint i...
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| Publicado no: | Sci Immunol |
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| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2024
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7616390/ https://ncbi.nlm.nih.gov/pubmed/39121196 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciimmunol.add4874 |
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