DOCK8 is critical for the survival and function of NKT cells

Patients with the dedicator of cytokinesis 8 (DOCK8) immunodeficiency syndrome suffer from recurrent viral and bacterial infections, hyper–immunoglobulin E levels, eczema, and greater susceptibility to cancer. Because natural killer T (NKT) cells have been implicated in these diseases, we asked if t...

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Detalhes bibliográficos
Main Authors: Crawford, Greg, Enders, Anselm, Gileadi, Uzi, Stankovic, Sanda, Zhang, Qian, Lambe, Teresa, Crockford, Tanya L., Lockstone, Helen E., Freeman, Alexandra, Arkwright, Peter D., Smart, Joanne M., Ma, Cindy S., Tangye, Stuart G., Goodnow, Christopher C., Cerundolo, Vincenzo, Godfrey, Dale I., Su, Helen C., Randall, Katrina L., Cornall, Richard J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2013
Assuntos:
Immunobiology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3778549/
https://ncbi.nlm.nih.gov/pubmed/23929855
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2013-02-482331
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