DOCK8 is critical for the survival and function of NKT cells

Patients with the dedicator of cytokinesis 8 (DOCK8) immunodeficiency syndrome suffer from recurrent viral and bacterial infections, hyper–immunoglobulin E levels, eczema, and greater susceptibility to cancer. Because natural killer T (NKT) cells have been implicated in these diseases, we asked if t...

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Hlavní autoři: Crawford, Greg, Enders, Anselm, Gileadi, Uzi, Stankovic, Sanda, Zhang, Qian, Lambe, Teresa, Crockford, Tanya L., Lockstone, Helen E., Freeman, Alexandra, Arkwright, Peter D., Smart, Joanne M., Ma, Cindy S., Tangye, Stuart G., Goodnow, Christopher C., Cerundolo, Vincenzo, Godfrey, Dale I., Su, Helen C., Randall, Katrina L., Cornall, Richard J.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society of Hematology 2013
Témata:
Immunobiology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3778549/
https://ncbi.nlm.nih.gov/pubmed/23929855
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2013-02-482331
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