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Mutation of Fnip1 is associated with B-cell deficiency, cardiomyopathy, and elevated AMPK activity
Folliculin (FLCN) is a tumor-suppressor protein mutated in the Birt–Hogg–Dubé (BHD) syndrome, which associates with two paralogous proteins, folliculin-interacting protein (FNIP)1 and FNIP2, forming a complex that interacts with the AMP-activated protein kinase (AMPK). Although it is clear that this...
में बचाया:
| में प्रकाशित: | Proc Natl Acad Sci U S A |
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| मुख्य लेखकों: | , , , , , , , , , , , , , , , , , , , |
| स्वरूप: | Artigo |
| भाषा: | Inglês |
| प्रकाशित: |
National Academy of Sciences
2016
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| विषय: | |
| ऑनलाइन पहुंच: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4932993/ https://ncbi.nlm.nih.gov/pubmed/27303042 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1607592113 |
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