Benzimidazole derivative small-molecule 991 enhances AMPK activity and glucose uptake induced by AICAR or contraction in skeletal muscle

AMP-activated protein kinase (AMPK) plays diverse roles and coordinates complex metabolic pathways for maintenance of energy homeostasis. This could be explained by the fact that AMPK exists as multiple heterotrimer complexes comprising a catalytic α-subunit (α1 and α2) and regulatory β (β1 and β2)-...

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Publicado no:Am J Physiol Endocrinol Metab
Main Authors: Bultot, Laurent, Jensen, Thomas E., Lai, Yu-Chiang, Madsen, Agnete L. B., Collodet, Caterina, Kviklyte, Samanta, Deak, Maria, Yavari, Arash, Foretz, Marc, Ghaffari, Sahar, Bellahcene, Mohamed, Ashrafian, Houman, Rider, Mark H., Richter, Erik A., Sakamoto, Kei
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2016
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5241553/
https://ncbi.nlm.nih.gov/pubmed/27577855
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpendo.00237.2016
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