AMPK promotes induction of the tumor suppressor FLCN through activation of TFEB independently of mTOR

AMPK is a central regulator of energy homeostasis. AMPK not only elicits acute metabolic responses but also promotes metabolic reprogramming and adaptations in the long-term through regulation of specific transcription factors and coactivators. We performed a whole-genome transcriptome profiling in...

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Опубликовано в: :FASEB J
Главные авторы: Collodet, Caterina, Foretz, Marc, Deak, Maria, Bultot, Laurent, Metairon, Sylviane, Viollet, Benoit, Lefebvre, Gregory, Raymond, Frederic, Parisi, Alice, Civiletto, Gabriele, Gut, Philipp, Descombes, Patrick, Sakamoto, Kei
Формат: Artigo
Язык:Inglês
Опубликовано: Federation of American Societies for Experimental Biology 2019
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Research
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6902666/
https://ncbi.nlm.nih.gov/pubmed/31404503
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.201900841R
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