Discrete mechanisms of mTOR and cell cycle regulation by AMPK agonists independent of AMPK

The multifunctional AMPK-activated protein kinase (AMPK) is an evolutionarily conserved energy sensor that plays an important role in cell proliferation, growth, and survival. It remains unclear whether AMPK functions as a tumor suppressor or a contextual oncogene. This is because although on one ha...

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Библиографические подробности
Главные авторы: Liu, Xiaona, Chhipa, Rishi Raj, Pooya, Shabnam, Wortman, Matthew, Yachyshin, Sara, Chow, Lionel M. L., Kumar, Ashish, Zhou, Xuan, Sun, Ying, Quinn, Brian, McPherson, Christopher, Warnick, Ronald E., Kendler, Ady, Giri, Shailendra, Poels, Jeroen, Norga, Koenraad, Viollet, Benoit, Grabowski, Gregory A., Dasgupta, Biplab
Формат: Artigo
Язык:Inglês
Опубликовано: National Academy of Sciences 2014
Предметы:
PNAS Plus
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3910576/
https://ncbi.nlm.nih.gov/pubmed/24474794
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1311121111
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