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Discrete mechanisms of mTOR and cell cycle regulation by AMPK agonists independent of AMPK

The multifunctional AMPK-activated protein kinase (AMPK) is an evolutionarily conserved energy sensor that plays an important role in cell proliferation, growth, and survival. It remains unclear whether AMPK functions as a tumor suppressor or a contextual oncogene. This is because although on one ha...

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Bibliografische gegevens
Hoofdauteurs: Liu, Xiaona, Chhipa, Rishi Raj, Pooya, Shabnam, Wortman, Matthew, Yachyshin, Sara, Chow, Lionel M. L., Kumar, Ashish, Zhou, Xuan, Sun, Ying, Quinn, Brian, McPherson, Christopher, Warnick, Ronald E., Kendler, Ady, Giri, Shailendra, Poels, Jeroen, Norga, Koenraad, Viollet, Benoit, Grabowski, Gregory A., Dasgupta, Biplab
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: National Academy of Sciences 2014
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3910576/
https://ncbi.nlm.nih.gov/pubmed/24474794
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1311121111
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