Discrete mechanisms of mTOR and cell cycle regulation by AMPK agonists independent of AMPK

The multifunctional AMPK-activated protein kinase (AMPK) is an evolutionarily conserved energy sensor that plays an important role in cell proliferation, growth, and survival. It remains unclear whether AMPK functions as a tumor suppressor or a contextual oncogene. This is because although on one ha...

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Bibliographische Detailangaben
Hauptverfasser: Liu, Xiaona, Chhipa, Rishi Raj, Pooya, Shabnam, Wortman, Matthew, Yachyshin, Sara, Chow, Lionel M. L., Kumar, Ashish, Zhou, Xuan, Sun, Ying, Quinn, Brian, McPherson, Christopher, Warnick, Ronald E., Kendler, Ady, Giri, Shailendra, Poels, Jeroen, Norga, Koenraad, Viollet, Benoit, Grabowski, Gregory A., Dasgupta, Biplab
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 2014
Schlagworte:
PNAS Plus
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3910576/
https://ncbi.nlm.nih.gov/pubmed/24474794
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1311121111
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