Targeting histone lysine demethylases — Progress, challenges, and the future()

Por Thinnes, Cyrille C., England, Katherine S., Kawamura, Akane, Chowdhury, Rasheduzzaman, Schofield, Christopher J., Hopkinson, Richard J.
Publicado no Biochim Biophys Acta Gene Regul Mech (2014)

A Novel Color Change Mechanism for Breast Cancer Biomarker Detection: Naphthoquinones as Specific Ligands of Human Arylamine N-Acetyltransferase 1

Por Laurieri, Nicola, Egleton, James E., Varney, Amy, Thinnes, Cyrille C., Quevedo, Camilo E., Seden, Peter T., Thompson, Sam, Rodrigues-Lima, Fernando, Dairou, Julien, Dupret, Jean-Marie, Russell, Angela J., Sim, Edith
Publicado em 2013

Therapeutic targeting of oxygen-sensing prolyl hydroxylases abrogates ATF4-dependent neuronal death and improves outcomes after brain hemorrhage in several rodent models

Por Karuppagounder, Saravanan S., Alim, Ishraq, Khim, Soah J., Bourassa, Megan W., Sleiman, Sama F., John, Roseleen, Thinnes, Cyrille C., Yeh, Tzu-Lan, Demetriades, Marina, Neitemeier, Sandra, Cruz, Dana, Gazaryan, Irina, Killilea, David W., Morgenstern, Lewis, Xi, Guohua, Keep, Richard F., Schallert, Timothy, Tappero, Ryan V., Zhong, Jian, Cho, Sunghee, Maxfield, Frederick R., Holman, Theodore R., Culmsee, Carsten, Fong, Guo-Hua, Su, Yijing, Ming, Guo-li, Song, Hongjun, Cave, John W., Schofield, Christopher J., Colbourne, Frederick, Coppola, Giovanni, Ratan, Rajiv R.
Publicado no Sci Transl Med (2016)

5-Carboxy-8-hydroxyquinoline is a Broad Spectrum 2-Oxoglutarate Oxygenase Inhibitor which Causes Iron Translocation

Por Hopkinson, Richard J., Tumber, Anthony, Yapp, Clarence, Chowdhury, Rasheduzzaman, Aik, WeiShen, Che, Ka Hing, Li, Xuan Shirley, Kristensen, Jan B. L., King, Oliver N. F., Chan, Mun Chiang, Yeoh, Kar Kheng, Choi, Hwanho, Walport, Louise J., Thinnes, Cyrille C., Bush, Jacob T., Lejeune, Clarisse, Rydzik, Anna M., Rose, Nathan R., Bagg, Eleanor A., McDonough, Michael A., Krojer, Tobias, Yue, Wyatt W., Ng, Stanley S., Olsen, Lars, Brennan, Paul E., Oppermann, Udo, Muller-Knapp, Susanne, Klose, Robert J., Ratcliffe, Peter J., Schofield, Christopher J., Kawamura, Akane
Publicado no Chem Sci (2013)