Drug metabolism and antibiotic resistance in micro‐organisms

Yazar: Sim, Edith, Ryan, Ali
Yayımlandı Br J Pharmacol (2017)

Kinetic characterisation of arylamine N-acetyltransferase from Pseudomonas aeruginosa

Yazar: Westwood, Isaac M, Sim, Edith
Baskı/Yayın Bilgisi 2007

Structure and transcriptional regulation of the Nat2 gene encoding for the drug-metabolizing enzyme arylamine N-acetyltransferase type 2 in mice.

Yazar: Boukouvala, Sotiria, Price, Naomi, Plant, Kathryn E, Sim, Edith
Baskı/Yayın Bilgisi 2003

Cloning and Characterization of Arylamine N-Acetyltransferase Genes from Mycobacterium smegmatis and Mycobacterium tuberculosis: Increased Expression Results in Isoniazid Resistanc...

Yazar: Payton, Mark, Auty, Roy, Delgoda, Rupika, Everett, Martin, Sim, Edith
Baskı/Yayın Bilgisi 1999

NAT gene polymorphisms and susceptibility to Alzheimer's disease: identification of a novel NAT1 allelic variant

Yazar: Johnson, Nichola, Bell, Peter, Jonovska, Vesna, Budge, Marc, Sim, Edith
Baskı/Yayın Bilgisi 2004

Binding of the anti-tubercular drug isoniazid to the arylamine N-acetyltransferase protein from Mycobacterium smegmatis

Yazar: Sandy, James, Holton, Simon, Fullam, Elizabeth, Sim, Edith, Noble, Martin
Baskı/Yayın Bilgisi 2005

Activation of nitrofurazone by azoreductases: multiple activities in one enzyme

Yazar: Ryan, Ali, Kaplan, Elise, Laurieri, Nicola, Lowe, Edward, Sim, Edith
Baskı/Yayın Bilgisi 2011

Deletion of a xenobiotic metabolizing gene in mice affects folate metabolism

Yazar: Wakefield, Larissa, Cornish, Valerie, Long, Hilary, Griffiths, William J., Sim, Edith
Baskı/Yayın Bilgisi 2007

Reaction mechanism of azoreductases suggests convergent evolution with quinone oxidoreductases

Yazar: Ryan, Ali, Wang, Chan-Ju, Laurieri, Nicola, Westwood, Isaac, Sim, Edith
Yayımlandı Protein Cell (2010)

Prospective virtual screening with Ultrafast Shape Recognition: the identification of novel inhibitors of arylamine N-acetyltransferases

Yazar: Ballester, Pedro J., Westwood, Isaac, Laurieri, Nicola, Sim, Edith, Richards, W. Graham
Baskı/Yayın Bilgisi 2010

Changes in consensus arylamine N-acetyltransferase (NAT) gene nomenclature

Yazar: Hein, David W., Boukouvala, Sotiria, Grant, Denis M., Minchin, Rodney F., Sim, Edith
Baskı/Yayın Bilgisi 2008

Purification of human C3b inactivator by monoclonal-antibody affinity chromatography

Yazar: Hsiung, Li-min, Barclay, A. Neil, Brandon, Malcolm R., Sim, Edith, Porter, Rodney R.
Baskı/Yayın Bilgisi 1982

Investigation of the catalytic triad of arylamine N-acetyltransferases: essential residues required for acetyl transfer to arylamines

Yazar: Sandy, James, Mushtaq, Adeel, Holton, Simon J., Schartau, Pamela, Noble, Martin E. M., Sim, Edith
Baskı/Yayın Bilgisi 2005

Mouse arylamine N-acetyltransferase 2 (Nat2) expression during embryogenesis: a potential marker for the developing neuroendocrine system

Yazar: Wakefield, Larissa, Cornish, Valerie, Long, Hilary, Kawamura, Akane, Zhang, Xiaoyan, Hein, David W., Sim, Edith
Baskı/Yayın Bilgisi 2008

Role of tyrosine 131 in the active site of paAzoR1, an azoreductase with specificity for the inflammatory bowel disease prodrug balsalazide

Yazar: Wang, Chan-Ju, Laurieri, Nicola, Abuhammad, Areej, Lowe, Edward, Westwood, Isaac, Ryan, Ali, Sim, Edith
Baskı/Yayın Bilgisi 2009

Probing the architecture of the Mycobacterium marinum arylamine N-acetyltransferase active site

Yazar: Abuhammad, Areej M., Lowe, Edward D., Fullam, Elizabeth, Noble, Martin, Garman, Elspeth F., Sim, Edith
Yayımlandı Protein Cell (2010)

Mouse N-acetyltransferase type 2, the homologue of human N-acetyltransferase type 1

Yazar: Kawamura, Akane, Westwood, Isaac, Wakefield, Larissa, Long, Hilary, Zhang, Naixia, Walters, Kylie, Redfield, Christina, Sim, Edith
Baskı/Yayın Bilgisi 2008

Downregulation of Hepatic Acetylation of Drugs in Chronic Renal Failure

Yazar: Simard, Emilie, Naud, Judith, Michaud, Josée, Leblond, Francois A., Bonnardeaux, Alain, Guillemette, Chantal, Sim, Edith, Pichette, Vincent
Baskı/Yayın Bilgisi 2008

Comparative analysis of xenobiotic metabolising N-acetyltransferases from ten non-human primates as in vitro models of human homologues

Yazar: Tsirka, Theodora, Konstantopoulou, Maria, Sabbagh, Audrey, Crouau-Roy, Brigitte, Ryan, Ali, Sim, Edith, Boukouvala, Sotiria, Fakis, Giannoulis
Yayımlandı Sci Rep (2018)

Exploration of Piperidinols as Potential Antitubercular Agents

Yazar: Abuhammad, Areej, Fullam, Elizabeth, Bhakta, Sanjib, Russell, Angela J., Morris, Garrett M., Finn, Paul W., Sim, Edith
Yayımlandı Molecules (2014)