Investigation of the catalytic triad of arylamine N-acetyltransferases: essential residues required for acetyl transfer to arylamines

The NATs (arylamine N-acetyltransferases) are a well documented family of enzymes found in both prokaryotes and eukaryotes. NATs are responsible for the acetylation of a range of arylamine, arylhydrazine and hydrazine compounds. We present here an investigation into the catalytic triad of residues (...

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Bibliographic Details
Main Authors: Sandy, James, Mushtaq, Adeel, Holton, Simon J., Schartau, Pamela, Noble, Martin E. M., Sim, Edith
Format: Artigo
Language:Inglês
Published: Portland Press Ltd. 2005
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1184567/
https://ncbi.nlm.nih.gov/pubmed/15869465
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20050277
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