Discrimination between bacterial species by ratiometric analysis of their carbohydrate binding profile

Por Otten, Lucienne, Fullam, Elizabeth, Gibson, Matthew I.
Publicado no Mol Biosyst (2016)

Targeting extracellular glycans: tuning multimeric boronic acids for pathogen-selective killing of Mycobacterium tuberculosis

Por Guy, Collette S., Gibson, Matthew I., Fullam, Elizabeth
Publicado no Chem Sci (2019)

Structural and functional analysis of the solute-binding protein UspC from Mycobacterium tuberculosis that is specific for amino sugars

Por Fullam, Elizabeth, Prokes, Ivan, Fütterer, Klaus, Besra, Gurdyal S.
Publicado no Open Biol (2016)

Binding of the anti-tubercular drug isoniazid to the arylamine N-acetyltransferase protein from Mycobacterium smegmatis

Por Sandy, James, Holton, Simon, Fullam, Elizabeth, Sim, Edith, Noble, Martin
Publicado em 2005

Structure and function of the transketolase from Mycobacterium tuberculosis and comparison with the human enzyme

Por Fullam, Elizabeth, Pojer, Florence, Bergfors, Terese, Jones, T. Alwyn, Cole, Stewart T.
Publicado em 2012

A GFP-strategy for efficient recombinant protein overexpression and purification in Mycobacterium smegmatis

Por Radhakrishnan, Anjana, Furze, Christopher M., Ahangar, Mohd Syed, Fullam, Elizabeth
Publicado no RSC Adv (2018)

Probing the architecture of the Mycobacterium marinum arylamine N-acetyltransferase active site

Por Abuhammad, Areej M., Lowe, Edward D., Fullam, Elizabeth, Noble, Martin, Garman, Elspeth F., Sim, Edith
Publicado no Protein Cell (2010)

Multivalent Antimicrobial Polymer Nanoparticles Target Mycobacteria and Gram-Negative Bacteria by Distinct Mechanisms

Por Richards, Sarah-Jane, Isufi, Klea, Wilkins, Laura E., Lipecki, Julia, Fullam, Elizabeth, Gibson, Matthew I.
Publicado no Biomacromolecules (2017)

Structural Basis of Glycerophosphodiester Recognition by the Mycobacterium tuberculosis Substrate-Binding Protein UgpB

Por Fenn, Jonathan S., Nepravishta, Ridvan, Guy, Collette S., Harrison, James, Angulo, Jesus, Cameron, Alexander D., Fullam, Elizabeth
Publicado no ACS Chem Biol (2019)

Exploration of Piperidinols as Potential Antitubercular Agents

Por Abuhammad, Areej, Fullam, Elizabeth, Bhakta, Sanjib, Russell, Angela J., Morris, Garrett M., Finn, Paul W., Sim, Edith
Publicado no Molecules (2014)

Arylamine N-Acetyltransferases in Mycobacteria

Por Sim, Edith, Sandy, James, Evangelopoulos, Dimitrios, Fullam, Elizabeth, Bhakta, Sanjib, Westwood, Isaac, Krylova, Anna, Lack, Nathan, Noble, Martin
Publicado em 2008

Structural and functional determination of homologs of the Mycobacterium tuberculosis N-acetylglucosamine-6-phosphate deacetylase (NagA)

Por Ahangar, Mohd Syed, Furze, Christopher M., Guy, Collette S., Cooper, Charlotte, Maskew, Kathryn S., Graham, Ben, Cameron, Alexander D., Fullam, Elizabeth
Publicado no J Biol Chem (2018)

Evaluation of the Antimicrobial Activity of Cationic Polymers against Mycobacteria: Toward Antitubercular Macromolecules

Por Phillips, Daniel J., Harrison, James, Richards, Sarah-Jane, Mitchell, Daniel E., Tichauer, Esther, Hubbard, Alasdair T. M., Guy, Collette, Hands-Portman, Ian, Fullam, Elizabeth, Gibson, Matthew I.
Publicado no Biomacromolecules (2017)

Identification of the anti‐mycobacterial functional properties of piperidinol derivatives

Por Guy, Collette S, Tichauer, Esther, Kay, Gemma L, Phillips, Daniel J, Bailey, Trisha L, Harrison, James, Furze, Christopher M, Millard, Andrew D, Gibson, Matthew I, Pallen, Mark J, Fullam, Elizabeth
Publicado no Br J Pharmacol (2017)

Identification of arylamine N-acetyltransferase inhibitors as an approach towards novel anti-tuberculars

Por Westwood, Isaac M., Bhakta, Sanjib, Russell, Angela J., Fullam, Elizabeth, Anderton, Matthew C., Kawamura, Akane, Mulvaney, Andrew W., Vickers, Richard J., Bhowruth, Veemal, Besra, Gurdyal S., Lalvani, Ajit, Davies, Stephen G., Sim, Edith
Publicado no Protein Cell (2010)

Structural basis of trehalose recognition by the mycobacterial LpqY-SugABC transporter

Por Furze, Christopher M., Delso, Ignacio, Casal, Enriqueta, Guy, Collette S., Seddon, Chloe, Brown, Chelsea M., Parker, Hadyn L., Radhakrishnan, Anjana, Pacheco-Gomez, Raul, Stansfeld, Phillip J., Angulo, Jesus, Cameron, Alexander D., Fullam, Elizabeth
Publicado no J Biol Chem (2021)

Piperidinols That Show Anti-Tubercular Activity as Inhibitors of Arylamine N-Acetyltransferase: An Essential Enzyme for Mycobacterial Survival Inside Macrophages

Por Abuhammad, Areej, Fullam, Elizabeth, Lowe, Edward D., Staunton, David, Kawamura, Akane, Westwood, Isaac M., Bhakta, Sanjib, Garner, Alun Christopher, Wilson, David L., Seden, Peter T., Davies, Stephen G., Russell, Angela J., Garman, Elspeth F., Sim, Edith
Publicado em 2012

Structural basis for benzothiazinone-mediated killing of Mycobacterium tuberculosis

Por Neres, João, Pojer, Florence, Molteni, Elisabetta, Chiarelli, Laurent R., Dhar, Neeraj, Boy-Röttger, Stefanie, Buroni, Silvia, Fullam, Elizabeth, Degiacomi, Giulia, Lucarelli, Anna Paola, Read, Randy J., Zanoni, Giuseppe, Edmondson, Dale E., De Rossi, Edda, Pasca, Maria Rosalia, McKinney, John D., Dyson, Paul J., Riccardi, Giovanna, Mattevi, Andrea, Cole, Stewart T., Binda, Claudia
Publicado em 2012

Benzothiazinones Kill Mycobacterium tuberculosis by Blocking Arabinan Synthesis

Por Makarov, Vadim, Manina, Giulia, Mikusova, Katarina, Möllmann, Ute, Ryabova, Olga, Saint-Joanis, Brigitte, Dhar, Neeraj, Pasca, Maria Rosalia, Buroni, Silvia, Lucarelli, Anna Paola, Milano, Anna, De Rossi, Edda, Belanova, Martina, Bobovska, Adela, Dianiskova, Petronela, Kordulakova, Jana, Sala, Claudia, Fullam, Elizabeth, Schneider, Patricia, McKinney, John D., Brodin, Priscille, Christophe, Thierry, Waddell, Simon, Butcher, Philip, Albrethsen, Jakob, Rosenkrands, Ida, Brosch, Roland, Nandi, Vrinda, Bharath, Sowmya, Gaonkar, Sheshagiri, Shandil, Radha K., Balasubramanian, Venkataraman, Balganesh, Tanjore, Tyagi, Sandeep, Grosset, Jacques, Riccardi, Giovanna, Cole, Stewart T.
Publicado em 2009