Expression, purification, crystallization and preliminary crystallographic analysis of the mouse transcription factor MafB in complex with its DNA-recognition motif Cmare

par Textor, Larissa C., Wilmanns, Matthias, Holton, Simon J.
Publié 2007

Binding of the anti-tubercular drug isoniazid to the arylamine N-acetyltransferase protein from Mycobacterium smegmatis

par Sandy, James, Holton, Simon, Fullam, Elizabeth, Sim, Edith, Noble, Martin
Publié 2005

WXG100 Protein Superfamily Consists of Three Subfamilies and Exhibits an α-Helical C-Terminal Conserved Residue Pattern

par Poulsen, Christian, Panjikar, Santosh, Holton, Simon J., Wilmanns, Matthias, Song, Young-Hwa
Publié 2014

Investigation of the catalytic triad of arylamine N-acetyltransferases: essential residues required for acetyl transfer to arylamines

par Sandy, James, Mushtaq, Adeel, Holton, Simon J., Schartau, Pamela, Noble, Martin E. M., Sim, Edith
Publié 2005

Structure of Mesorhizobium loti arylamine N-acetyltransferase 1

par Holton, Simon J., Dairou, Julien, Sandy, James, Rodrigues-Lima, Fernando, Dupret, Jean-Marie, Noble, Martin E. M., Sim, Edith
Publié 2004

Expression, purification, characterization and structure of Pseudomonas aeruginosa arylamine N-acetyltransferase

par Westwood, Isaac M., Holton, Simon J., Rodrigues-Lima, Fernando, Dupret, Jean-Marie, Bhakta, Sanjib, Noble, Martin E. M., Sim, Edith
Publié 2005

The peroxisomal receptor Pex19p forms a helical mPTS recognition domain

par Schueller, Nicole, Holton, Simon J, Fodor, Krisztian, Milewski, Morlin, Konarev, Petr, Stanley, Will A, Wolf, Janina, Erdmann, Ralf, Schliebs, Wolfgang, Song, Young-Hwa, Wilmanns, Matthias
Publié 2010

Functional and Structural Characterization of Bub3·BubR1 Interactions Required for Spindle Assembly Checkpoint Signaling in Human Cells

par Prinz, Florian, Puetter, Vera, Holton, Simon J., Andres, Dorothee, Stegmann, Christian M., Kwiatkowski, Dennis, Prechtl, Stefan, Petersen, Kirstin, Beckmann, Georg, Kreft, Bertolt, Mumberg, Dominik, Fernández-Montalván, Amaury
Publié dans J Biol Chem (2016)

ATAD2 is an epigenetic reader of newly synthesized histone marks during DNA replication

par Koo, Seong Joo, Fernández-Montalván, Amaury E., Badock, Volker, Ott, Christopher J., Holton, Simon J., von Ahsen, Oliver, Toedling, Joern, Vittori, Sarah, Bradner, James E., Gorjánácz, Mátyás
Publié dans Oncotarget (2016)

Benzoisoquinolinediones as Potent and Selective Inhibitors of BRPF2 and TAF1/TAF1L Bromodomains

par Bouché, Léa, Christ, Clara D., Siegel, Stephan, Fernández-Montalván, Amaury E., Holton, Simon J., Fedorov, Oleg, ter Laak, Antonius, Sugawara, Tatsuo, Stöckigt, Detlef, Tallant, Cynthia, Bennett, James, Monteiro, Octovia, Díaz-Sáez, Laura, Siejka, Paulina, Meier, Julia, Pütter, Vera, Weiske, Jörg, Müller, Susanne, Huber, Kilian V. M., Hartung, Ingo V., Haendler, Bernard
Publié dans J Med Chem (2017)

Isoform-Selective ATAD2 Chemical Probe with Novel Chemical Structure and Unusual Mode of Action

par Fernández-Montalván, Amaury E., Berger, Markus, Kuropka, Benno, Koo, Seong Joo, Badock, Volker, Weiske, Joerg, Puetter, Vera, Holton, Simon J., Stöckigt, Detlef, ter Laak, Antonius, Centrella, Paolo A., Clark, Matthew A., Dumelin, Christoph E., Sigel, Eric A., Soutter, Holly H., Troast, Dawn M., Zhang, Ying, Cuozzo, John W., Keefe, Anthony D., Roche, Didier, Rodeschini, Vincent, Chaikuad, Apirat, Díaz-Sáez, Laura, Bennett, James M., Fedorov, Oleg, Huber, Kilian V. M., Hübner, Jan, Weinmann, Hilmar, Hartung, Ingo V., Gorjánácz, Mátyás
Publié dans ACS Chem Biol (2017)