New Class of Bacterial Phenylalanyl-tRNA Synthetase Inhibitors with High Potency and Broad-Spectrum Activity

Por Beyer, Dieter, Kroll, Hein-Peter, Endermann, Rainer, Schiffer, Guido, Siegel, Stephan, Bauser, Marcus, Pohlmann, Jens, Brands, Michael, Ziegelbauer, Karl, Haebich, Dieter, Eymann, Christine, Brötz-Oesterhelt, Heike
Publicado em 2004

BET inhibition is an effective approach against KRAS-driven PDAC and NSCLC

Por Jauset, Toni, Massó-Vallés, Daniel, Martínez-Martín, Sandra, Beaulieu, Marie-Eve, Foradada, Laia, Fiorentino, Francesco Paolo, Yokota, Jun, Haendler, Bernard, Siegel, Stephan, Whitfield, Jonathan R., Soucek, Laura
Publicado no Oncotarget (2018)

Benzoisoquinolinediones as Potent and Selective Inhibitors of BRPF2 and TAF1/TAF1L Bromodomains

Por Bouché, Léa, Christ, Clara D., Siegel, Stephan, Fernández-Montalván, Amaury E., Holton, Simon J., Fedorov, Oleg, ter Laak, Antonius, Sugawara, Tatsuo, Stöckigt, Detlef, Tallant, Cynthia, Bennett, James, Monteiro, Octovia, Díaz-Sáez, Laura, Siejka, Paulina, Meier, Julia, Pütter, Vera, Weiske, Jörg, Müller, Susanne, Huber, Kilian V. M., Hartung, Ingo V., Haendler, Bernard
Publicado no J Med Chem (2017)