Functional and Structural Characterization of Bub3·BubR1 Interactions Required for Spindle Assembly Checkpoint Signaling in Human Cells

The spindle assembly checkpoint (SAC) is an essential safeguarding mechanism devised to ensure equal chromosome distribution in daughter cells upon mitosis. The proteins Bub3 and BubR1 are key components of the mitotic checkpoint complex, an essential part of the molecular machinery on which the SAC...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Prinz, Florian, Puetter, Vera, Holton, Simon J., Andres, Dorothee, Stegmann, Christian M., Kwiatkowski, Dennis, Prechtl, Stefan, Petersen, Kirstin, Beckmann, Georg, Kreft, Bertolt, Mumberg, Dominik, Fernández-Montalván, Amaury
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2016
Assuntos:
Protein Structure and Folding
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4900272/
https://ncbi.nlm.nih.gov/pubmed/27030009
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.702142
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