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TAp73 regulates the spindle assembly checkpoint by modulating BubR1 activity

The role of various p73 isoforms in tumorigenesis has been controversial. However, as we have recently shown, the generation of TAp73-deficient (TAp73(−/−)) mice reveals that TAp73 isoforms exert tumor-suppressive functions, indicating an emerging role for Trp-73 in the maintenance of genomic stabil...

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Bibliographische Detailangaben
Hauptverfasser: Tomasini, Richard, Tsuchihara, Katsuya, Tsuda, Chiharu, Lau, Suzanne K., Wilhelm, Margareta, Rufini, Alessandro, Tsao, Ming-sound, Iovanna, Juan L., Jurisicova, Andrea, Melino, Gerry, Mak, Tak W.
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 2009
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2621249/
https://ncbi.nlm.nih.gov/pubmed/19139399
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0812096106
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