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TAp73 regulates the spindle assembly checkpoint by modulating BubR1 activity

The role of various p73 isoforms in tumorigenesis has been controversial. However, as we have recently shown, the generation of TAp73-deficient (TAp73(−/−)) mice reveals that TAp73 isoforms exert tumor-suppressive functions, indicating an emerging role for Trp-73 in the maintenance of genomic stabil...

詳細記述

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書誌詳細
主要な著者: Tomasini, Richard, Tsuchihara, Katsuya, Tsuda, Chiharu, Lau, Suzanne K., Wilhelm, Margareta, Rufini, Alessandro, Tsao, Ming-sound, Iovanna, Juan L., Jurisicova, Andrea, Melino, Gerry, Mak, Tak W.
フォーマット: Artigo
言語:Inglês
出版事項: National Academy of Sciences 2009
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2621249/
https://ncbi.nlm.nih.gov/pubmed/19139399
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0812096106
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