TAp73 regulates the spindle assembly checkpoint by modulating BubR1 activity

The role of various p73 isoforms in tumorigenesis has been controversial. However, as we have recently shown, the generation of TAp73-deficient (TAp73(−/−)) mice reveals that TAp73 isoforms exert tumor-suppressive functions, indicating an emerging role for Trp-73 in the maintenance of genomic stabil...

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Dettagli Bibliografici
Autori principali: Tomasini, Richard, Tsuchihara, Katsuya, Tsuda, Chiharu, Lau, Suzanne K., Wilhelm, Margareta, Rufini, Alessandro, Tsao, Ming-sound, Iovanna, Juan L., Jurisicova, Andrea, Melino, Gerry, Mak, Tak W.
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2009
Soggetti:
Biological Sciences
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2621249/
https://ncbi.nlm.nih.gov/pubmed/19139399
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0812096106
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