Modeling cancer using patient-derived induced pluripotent stem cells to understand development of childhood malignancies

door Marin Navarro, Ana, Susanto, Evelyn, Falk, Anna, Wilhelm, Margareta
Gepubliceerd in Cell Death Discov (2018)

ΔNp73 enhances HIF-1α protein stability through repression of the ECV complex

door Stantic, Marina, Wolfsberger, Johanna, Sakil, Habib A. M., Wilhelm, Margareta T.
Gepubliceerd in Oncogene (2018)

The p53-induced mouse zinc finger protein wig-1 binds double-stranded RNA with high affinity

door Méndez-Vidal, Cristina, Wilhelm, Margareta T., Hellborg, Fredrik, Qian, Wang, Wiman, Klas G.
Gepubliceerd in 2002

MYC proteins promote neuronal differentiation by controlling the mode of progenitor cell division

door Zinin, Nikolay, Adameyko, Igor, Wilhelm, Margareta, Fritz, Nicolas, Uhlén, Per, Ernfors, Patrik, Henriksson, Marie Arsenian
Gepubliceerd in 2014

ΔNp73 regulates the expression of the multidrug-resistance genes ABCB1 and ABCB5 in breast cancer and melanoma cells - a short report

door Sakil, Habib A. M., Stantic, Marina, Wolfsberger, Johanna, Brage, Suzanne Egyhazi, Hansson, Johan, Wilhelm, Margareta T.
Gepubliceerd in Cell Oncol (Dordr) (2017)

Combining ERBB family and MET inhibitors is an effective therapeutic strategy in cutaneous malignant melanoma independent of BRAF/NRAS mutation status

door Das, Ishani, Wilhelm, Margareta, Höiom, Veronica, Franco Marquez, Rodolfo, Costa Svedman, Fernanda, Hansson, Johan, Tuominen, Rainer, Egyhàzi Brage, Suzanne
Gepubliceerd in Cell Death Dis (2019)

p53 controls genomic stability and temporal differentiation of human neural stem cells and affects neural organization in human brain organoids

door Marin Navarro, Ana, Pronk, Robin Johan, van der Geest, Astrid Tjitske, Oliynyk, Ganna, Nordgren, Ann, Arsenian-Henriksson, Marie, Falk, Anna, Wilhelm, Margareta
Gepubliceerd in Cell Death Dis (2020)

The p53 target Wig-1 regulates p53 mRNA stability through an AU-rich element

door Vilborg, Anna, Glahder, Jacob A., Wilhelm, Margareta T., Bersani, Cinzia, Corcoran, Martin, Mahmoudi, Salah, Rosenstierne, Maiken, Grandér, Dan, Farnebo, Marianne, Norrild, Bodil, Wiman, Klas G.
Gepubliceerd in 2009

TAp73 regulates the spindle assembly checkpoint by modulating BubR1 activity

door Tomasini, Richard, Tsuchihara, Katsuya, Tsuda, Chiharu, Lau, Suzanne K., Wilhelm, Margareta, Rufini, Alessandro, Tsao, Ming-sound, Iovanna, Juan L., Jurisicova, Andrea, Melino, Gerry, Mak, Tak W.
Gepubliceerd in 2009

TAp73 suppresses tumor angiogenesis through repression of proangiogenic cytokines and HIF-1α activity

door Stantic, Marina, Sakil, Habib A. M., Zirath, Hanna, Fang, Trixy, Sanz, Gema, Fernandez-Woodbridge, Alejandro, Marin, Ana, Susanto, Evelyn, Mak, Tak W., Arsenian Henriksson, Marie, Wilhelm, Margareta T.
Gepubliceerd in Proc Natl Acad Sci U S A (2015)

TAp73 represses NF-κB–mediated recruitment of tumor-associated macrophages in breast cancer

door Wolfsberger, Johanna, Sakil, Habib A. M., Zhou, Leilei, van Bree, Niek, Baldisseri, Elena, de Souza Ferreira, Sabrina, Zubillaga, Veronica, Stantic, Marina, Fritz, Nicolas, Hartman, Johan, Rolny, Charlotte, Wilhelm, Margareta T.
Gepubliceerd in Proc Natl Acad Sci U S A (2021)

Isoform-specific p73 knockout mice reveal a novel role for ΔNp73 in the DNA damage response pathway

door Wilhelm, Margareta T., Rufini, Alessandro, Wetzel, Monica K., Tsuchihara, Katsuya, Inoue, Satoshi, Tomasini, Richard, Itie-Youten, Annick, Wakeham, Andrew, Arsenian-Henriksson, Marie, Melino, Gerry, Kaplan, David R., Miller, Freda D., Mak, Tak W.
Gepubliceerd in 2010

TAp73 knockout shows genomic instability with infertility and tumor suppressor functions

door Tomasini, Richard, Tsuchihara, Katsuya, Wilhelm, Margareta, Fujitani, Masashi, Rufini, Alessandro, Cheung, Carol C., Khan, Fatima, Itie-Youten, Annick, Wakeham, Andrew, Tsao, Ming-sound, Iovanna, Juan L., Squire, Jeremy, Jurisica, Igor, Kaplan, David, Melino, Gerry, Jurisicova, Andrea, Mak, Tak W.
Gepubliceerd in 2008

Modeling SHH-driven medulloblastoma with patient iPS cell-derived neural stem cells

door Susanto, Evelyn, Marin Navarro, Ana, Zhou, Leilei, Sundström, Anders, van Bree, Niek, Stantic, Marina, Moslem, Mohsen, Tailor, Jignesh, Rietdijk, Jonne, Zubillaga, Veronica, Hübner, Jens-Martin, Weishaupt, Holger, Wolfsberger, Johanna, Alafuzoff, Irina, Nordgren, Ann, Magnaldo, Thierry, Siesjö, Peter, Johnsen, John Inge, Kool, Marcel, Tammimies, Kristiina, Darabi, Anna, Swartling, Fredrik J., Falk, Anna, Wilhelm, Margareta
Gepubliceerd in Proc Natl Acad Sci U S A (2020)