25 years of p53 research

av Hainaut, Pierre., Wiman, Klas G.
Publicerad 2005

p53 in the clinics

av Hainaut, Pierre., Olivier, Magali., Wiman, Klas G.
Publicerad 2013

Reactivation of Mutant p53 through Interaction of a C-Terminal Peptide with the Core Domain

av Selivanova, Galina, Ryabchenko, Ludmila, Jansson, Emmelie, Iotsova, Violetta, Wiman, Klas G.
Publicerad 1999

The p53-induced mouse zinc finger protein wig-1 binds double-stranded RNA with high affinity

av Méndez-Vidal, Cristina, Wilhelm, Margareta T., Hellborg, Fredrik, Qian, Wang, Wiman, Klas G.
Publicerad 2002

APR-246 reactivates mutant p53 by targeting cysteines 124 and 277

av Zhang, Qiang, Bykov, Vladimir J. N., Wiman, Klas G., Zawacka-Pankau, Joanna
I publikationen Cell Death Dis (2018)

p53 as a hub in cellular redox regulation and therapeutic target in cancer

av Eriksson, Sofi E, Ceder, Sophia, Bykov, Vladimir J N, Wiman, Klas G
I publikationen J Mol Cell Biol (2019)

Correction: APR-246 reactivates mutant p53 by targeting cysteines 124 and 277

av Zhang, Qiang, Bykov, Vladimir J. N., Wiman, Klas G., Zawacka-Pankau, Joanna
I publikationen Cell Death Dis (2019)

PRIMA-1(MET) Inhibits Growth of Mouse Tumors Carrying Mutant p53

av Zache, Nicole, Lambert, Jeremy M. R., Wiman, Klas G., Bykov, Vladimir J. N.
I publikationen Cell Oncol (2008)

cMyc-p53 feedback mechanism regulates the dynamics of T lymphocytes in the immune response

av Madapura, Harsha S., Salamon, Daniel, Wiman, Klas G., Lain, Sonia, Klein, Eva, Nagy, Noémi
I publikationen Cell Cycle (2016)

Rescue of mutants of the tumor suppressor p53 in cancer cells by a designed peptide

av Issaeva, Natalia, Friedler, Assaf, Bozko, Przemyslaw, Wiman, Klas G., Fersht, Alan R., Selivanova, Galina
Publicerad 2003

Strong synergy with APR-246 and DNA-damaging drugs in primary cancer cells from patients with TP53 mutant High-Grade Serous ovarian cancer

av Fransson, Åsa, Glaessgen, Daria, Alfredsson, Jessica, Wiman, Klas G., Bajalica-Lagercrantz, Svetlana, Mohell, Nina
I publikationen J Ovarian Res (2016)

p53 contributes to T cell homeostasis through the induction of pro-apoptotic SAP

av Madapura, Harsha S., Salamon, Daniel, Wiman, Klas G., Lain, Sonia, Klein, George, Klein, Eva, Nagy, Noémi
Publicerad 2012

Targeting of Mutant p53 and the Cellular Redox Balance by APR-246 as a Strategy for Efficient Cancer Therapy

av Bykov, Vladimir J. N., Zhang, Qiang, Zhang, Meiqiongzi, Ceder, Sophia, Abrahmsen, Lars, Wiman, Klas G.
I publikationen Front Oncol (2016)

Synergistic Rescue of Nonsense Mutant Tumor Suppressor p53 by Combination Treatment with Aminoglycosides and Mdm2 Inhibitors

av Zhang, Meiqiongzi, Heldin, Angelos, Palomar-Siles, Mireia, Öhlin, Susanne, Bykov, Vladimir J. N., Wiman, Klas G.
I publikationen Front Oncol (2018)

WRAP53 Is Essential for Cajal Body Formation and for Targeting the Survival of Motor Neuron Complex to Cajal Bodies

av Mahmoudi, Salah, Henriksson, Sofia, Weibrecht, Irene, Smith, Stephen, Söderberg, Ola, Strömblad, Staffan, Wiman, Klas G., Farnebo, Marianne
Publicerad 2010

Correction: WRAP53 Is Essential for Cajal Body Formation and for Targeting the Survival of Motor Neuron Complex to Cajal Bodies

av Mahmoudi, Salah, Henriksson, Sofia, Weibrecht, Irene, Smith, Stephen, Söderberg, Ola, Strömblad, Staffan, Wiman, Klas G., Farnebo, Marianne
I publikationen PLoS Biol (2018)

The Mutant p53-Targeting Compound APR-246 Induces ROS-Modulating Genes in Breast Cancer Cells

av Synnott, Naoise C., Madden, Stephen F., Bykov, Vladimir J.N., Crown, John, Wiman, Klas G., Duffy, Michael J.
I publikationen Transl Oncol (2018)

PRIMA-1(MET )induces nucleolar translocation of Epstein-Barr virus-encoded EBNA-5 protein

av Stuber, György, Flaberg, Emilie, Petranyi, Gabor, Ötvös, Rita, Rökaeus, Nina, Kashuba, Elena, Wiman, Klas G, Klein, George, Szekely, Laszlo
Publicerad 2009

Reactivation of mutant p53 and induction of apoptosis in human tumor cells by maleimide analogs.

av Bykov, Vladimir J. N., Issaeva, Natalia, Zache, Nicole, Shilov, Alexandre, Hultcrantz, Monica, Bergman, Jan, Selivanova, Galina, Wiman, Klas G.
I publikationen J Biol Chem (2017)

Inhibition of the glutaredoxin and thioredoxin systems and ribonucleotide reductase by mutant p53-targeting compound APR-246

av Haffo, Lena, Lu, Jun, Bykov, Vladimir J. N., Martin, Sebastin S., Ren, Xiaoyuan, Coppo, Lucia, Wiman, Klas G., Holmgren, Arne
I publikationen Sci Rep (2018)