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p53 as a hub in cellular redox regulation and therapeutic target in cancer
The TP53 tumor suppressor gene encodes a DNA-binding transcription factor that regulates multiple cellular processes including cell growth and cell death. The ability of p53 to bind to DNA and activate transcription is tightly regulated by post-translational modifications and is dependent on a reduc...
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| I publikationen: | J Mol Cell Biol |
|---|---|
| Huvudupphovsmän: | , , , |
| Materialtyp: | Artigo |
| Språk: | Inglês |
| Publicerad: |
Oxford University Press
2019
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| Ämnen: | |
| Länkar: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6734141/ https://ncbi.nlm.nih.gov/pubmed/30892598 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jmcb/mjz005 |
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