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cMyc-p53 feedback mechanism regulates the dynamics of T lymphocytes in the immune response

Activation and proliferation of T cells are tightly regulated during the immune response. We show here that kinetics of proliferation of PHA activated T cells follows the expression of cMyc. Expression of p53 is also elevated and remains high several days after activation. To investigate the role of...

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Detalhes bibliográficos
Publicado no:Cell Cycle
Main Authors: Madapura, Harsha S., Salamon, Daniel, Wiman, Klas G., Lain, Sonia, Klein, Eva, Nagy, Noémi
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4889243/
https://ncbi.nlm.nih.gov/pubmed/26985633
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15384101.2016.1160975
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