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The effect of non-coding DNA variations on P53 and cMYC competitive inhibition at cis-overlapping motifs

Non-coding DNA variations play a critical role in increasing the risk for development of common complex diseases, and account for the majority of SNPs highly associated with cancer. However, it remains a challenge to identify etiologic variants and to predict their pathological effects on target gen...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Hum Mol Genet
Päätekijät: Kin, Katherine, Chen, Xi, Gonzalez-Garay, Manuel, Fakhouri, Walid D.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Oxford University Press 2016
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC6281388/
https://ncbi.nlm.nih.gov/pubmed/26908612
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddw030
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