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The effect of non-coding DNA variations on P53 and cMYC competitive inhibition at cis-overlapping motifs

Non-coding DNA variations play a critical role in increasing the risk for development of common complex diseases, and account for the majority of SNPs highly associated with cancer. However, it remains a challenge to identify etiologic variants and to predict their pathological effects on target gen...

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Detalhes bibliográficos
Publicado no:Hum Mol Genet
Main Authors: Kin, Katherine, Chen, Xi, Gonzalez-Garay, Manuel, Fakhouri, Walid D.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6281388/
https://ncbi.nlm.nih.gov/pubmed/26908612
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddw030
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