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Temporal Requirements of cMyc Protein for Reprogramming Mouse Fibroblasts
Exogenous expression of Oct4, Sox2, Klf4, and cMyc forces mammalian somatic cells to adopt molecular and phenotypic characteristics of embryonic stem cells, commencing with the required suppression of lineage-associated genes (e.g., Thy1 in mouse). Although omitting cMyc from the reprogramming cockt...
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| 主要な著者: | , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Hindawi Publishing Corporation
2012
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3350996/ https://ncbi.nlm.nih.gov/pubmed/22619682 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2012/541014 |
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