Temporal Requirements of cMyc Protein for Reprogramming Mouse Fibroblasts

Exogenous expression of Oct4, Sox2, Klf4, and cMyc forces mammalian somatic cells to adopt molecular and phenotypic characteristics of embryonic stem cells, commencing with the required suppression of lineage-associated genes (e.g., Thy1 in mouse). Although omitting cMyc from the reprogramming cockt...

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Detaylı Bibliyografya
Asıl Yazarlar: Heffernan, Corey, Sumer, Huseyin, Malaver-Ortega, Luis F., Verma, Paul J.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Hindawi Publishing Corporation 2012
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3350996/
https://ncbi.nlm.nih.gov/pubmed/22619682
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2012/541014
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