Modeling cancer using patient-derived induced pluripotent stem cells to understand development of childhood malignancies

Por Marin Navarro, Ana, Susanto, Evelyn, Falk, Anna, Wilhelm, Margareta
Publicado no Cell Death Discov (2018)

ΔNp73 enhances HIF-1α protein stability through repression of the ECV complex

Por Stantic, Marina, Wolfsberger, Johanna, Sakil, Habib A. M., Wilhelm, Margareta T.
Publicado no Oncogene (2018)

The p53-induced mouse zinc finger protein wig-1 binds double-stranded RNA with high affinity

Por Méndez-Vidal, Cristina, Wilhelm, Margareta T., Hellborg, Fredrik, Qian, Wang, Wiman, Klas G.
Publicado em 2002

MYC proteins promote neuronal differentiation by controlling the mode of progenitor cell division

Por Zinin, Nikolay, Adameyko, Igor, Wilhelm, Margareta, Fritz, Nicolas, Uhlén, Per, Ernfors, Patrik, Henriksson, Marie Arsenian
Publicado em 2014

ΔNp73 regulates the expression of the multidrug-resistance genes ABCB1 and ABCB5 in breast cancer and melanoma cells - a short report

Por Sakil, Habib A. M., Stantic, Marina, Wolfsberger, Johanna, Brage, Suzanne Egyhazi, Hansson, Johan, Wilhelm, Margareta T.
Publicado no Cell Oncol (Dordr) (2017)

Combining ERBB family and MET inhibitors is an effective therapeutic strategy in cutaneous malignant melanoma independent of BRAF/NRAS mutation status

Por Das, Ishani, Wilhelm, Margareta, Höiom, Veronica, Franco Marquez, Rodolfo, Costa Svedman, Fernanda, Hansson, Johan, Tuominen, Rainer, Egyhàzi Brage, Suzanne
Publicado no Cell Death Dis (2019)

p53 controls genomic stability and temporal differentiation of human neural stem cells and affects neural organization in human brain organoids

Por Marin Navarro, Ana, Pronk, Robin Johan, van der Geest, Astrid Tjitske, Oliynyk, Ganna, Nordgren, Ann, Arsenian-Henriksson, Marie, Falk, Anna, Wilhelm, Margareta
Publicado no Cell Death Dis (2020)

The p53 target Wig-1 regulates p53 mRNA stability through an AU-rich element

Por Vilborg, Anna, Glahder, Jacob A., Wilhelm, Margareta T., Bersani, Cinzia, Corcoran, Martin, Mahmoudi, Salah, Rosenstierne, Maiken, Grandér, Dan, Farnebo, Marianne, Norrild, Bodil, Wiman, Klas G.
Publicado em 2009

TAp73 regulates the spindle assembly checkpoint by modulating BubR1 activity

Por Tomasini, Richard, Tsuchihara, Katsuya, Tsuda, Chiharu, Lau, Suzanne K., Wilhelm, Margareta, Rufini, Alessandro, Tsao, Ming-sound, Iovanna, Juan L., Jurisicova, Andrea, Melino, Gerry, Mak, Tak W.
Publicado em 2009

TAp73 suppresses tumor angiogenesis through repression of proangiogenic cytokines and HIF-1α activity

Por Stantic, Marina, Sakil, Habib A. M., Zirath, Hanna, Fang, Trixy, Sanz, Gema, Fernandez-Woodbridge, Alejandro, Marin, Ana, Susanto, Evelyn, Mak, Tak W., Arsenian Henriksson, Marie, Wilhelm, Margareta T.
Publicado no Proc Natl Acad Sci U S A (2015)

TAp73 represses NF-κB–mediated recruitment of tumor-associated macrophages in breast cancer

Por Wolfsberger, Johanna, Sakil, Habib A. M., Zhou, Leilei, van Bree, Niek, Baldisseri, Elena, de Souza Ferreira, Sabrina, Zubillaga, Veronica, Stantic, Marina, Fritz, Nicolas, Hartman, Johan, Rolny, Charlotte, Wilhelm, Margareta T.
Publicado no Proc Natl Acad Sci U S A (2021)

Isoform-specific p73 knockout mice reveal a novel role for ΔNp73 in the DNA damage response pathway

Por Wilhelm, Margareta T., Rufini, Alessandro, Wetzel, Monica K., Tsuchihara, Katsuya, Inoue, Satoshi, Tomasini, Richard, Itie-Youten, Annick, Wakeham, Andrew, Arsenian-Henriksson, Marie, Melino, Gerry, Kaplan, David R., Miller, Freda D., Mak, Tak W.
Publicado em 2010

TAp73 knockout shows genomic instability with infertility and tumor suppressor functions

Por Tomasini, Richard, Tsuchihara, Katsuya, Wilhelm, Margareta, Fujitani, Masashi, Rufini, Alessandro, Cheung, Carol C., Khan, Fatima, Itie-Youten, Annick, Wakeham, Andrew, Tsao, Ming-sound, Iovanna, Juan L., Squire, Jeremy, Jurisica, Igor, Kaplan, David, Melino, Gerry, Jurisicova, Andrea, Mak, Tak W.
Publicado em 2008

Modeling SHH-driven medulloblastoma with patient iPS cell-derived neural stem cells

Por Susanto, Evelyn, Marin Navarro, Ana, Zhou, Leilei, Sundström, Anders, van Bree, Niek, Stantic, Marina, Moslem, Mohsen, Tailor, Jignesh, Rietdijk, Jonne, Zubillaga, Veronica, Hübner, Jens-Martin, Weishaupt, Holger, Wolfsberger, Johanna, Alafuzoff, Irina, Nordgren, Ann, Magnaldo, Thierry, Siesjö, Peter, Johnsen, John Inge, Kool, Marcel, Tammimies, Kristiina, Darabi, Anna, Swartling, Fredrik J., Falk, Anna, Wilhelm, Margareta
Publicado no Proc Natl Acad Sci U S A (2020)