Isoform-specific p73 knockout mice reveal a novel role for ΔNp73 in the DNA damage response pathway

Mice with a complete deficiency of p73 have severe neurological and immunological defects due to the absence of all TAp73 and ΔNp73 isoforms. As part of our ongoing program to distinguish the biological functions of these isoforms, we generated mice that are selectively deficient for the ΔNp73 isofo...

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Detalhes bibliográficos
Main Authors: Wilhelm, Margareta T., Rufini, Alessandro, Wetzel, Monica K., Tsuchihara, Katsuya, Inoue, Satoshi, Tomasini, Richard, Itie-Youten, Annick, Wakeham, Andrew, Arsenian-Henriksson, Marie, Melino, Gerry, Kaplan, David R., Miller, Freda D., Mak, Tak W.
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2010
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2841333/
https://ncbi.nlm.nih.gov/pubmed/20194434
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.1873910
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