Differential control of TAp73 and ΔNp73 protein stability by the ring finger ubiquitin ligase PIR2

p73 is a p53-related transcription factor with fundamental roles in development and tumor suppression. Transcription from two different promoters on the p73 gene results in generation of transcriptionally active TAp73 isoforms and dominant negative ΔNp73 isoforms with opposing pro- and anti-apoptoti...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: Sayan, Berna S., Yang, Ai Li, Conforti, Franco, Tucci, Paola, Piro, Maria Cristina, Browne, Gareth J., Agostini, Massimiliano, Bernardini, Sergio, Knight, Richard A., Mak, Tak W., Melino, Gerry
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 2010
Schlagworte:
Biological Sciences
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2919933/
https://ncbi.nlm.nih.gov/pubmed/20615966
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0911828107
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!

Ähnliche Einträge