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Differential control of TAp73 and ΔNp73 protein stability by the ring finger ubiquitin ligase PIR2
p73 is a p53-related transcription factor with fundamental roles in development and tumor suppression. Transcription from two different promoters on the p73 gene results in generation of transcriptionally active TAp73 isoforms and dominant negative ΔNp73 isoforms with opposing pro- and anti-apoptoti...
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| 主要な著者: | , , , , , , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
National Academy of Sciences
2010
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2919933/ https://ncbi.nlm.nih.gov/pubmed/20615966 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0911828107 |
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