TAp73 promotes anti-senescence-anabolism not proliferation

TAp73, a member of the p53 family, has been traditionally considered a tumor suppressor gene, but a recent report has claimed that it can promote cellular proliferation. This assumption is based on biochemical evidence of activation of anabolic metabolism, with enhanced pentose phosphate shunt (PPP)...

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Библиографические подробности
Опубликовано в: :Aging (Albany NY)
Главные авторы: Agostini, Massimiliano, Niklison-Chirou, Maria Victoria, Catani, Maria Valeria, Knight, Richard A., Melino, Gerry, Rufini, Alessandro
Формат: Artigo
Язык:Inglês
Опубликовано: Impact Journals LLC 2014
Предметы:
Research Paper
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4276786/
https://ncbi.nlm.nih.gov/pubmed/25554796
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