TAp73 suppresses tumor angiogenesis through repression of proangiogenic cytokines and HIF-1α activity

The p53-family member TAp73 is known to function as a tumor suppressor and regulates genomic integrity, cellular proliferation, and apoptosis; however, its role in tumor angiogenesis is poorly understood. Here we demonstrate that TAp73 regulates tumor angiogenesis through repression of proangiogenic...

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Détails bibliographiques
Publié dans:Proc Natl Acad Sci U S A
Auteurs principaux: Stantic, Marina, Sakil, Habib A. M., Zirath, Hanna, Fang, Trixy, Sanz, Gema, Fernandez-Woodbridge, Alejandro, Marin, Ana, Susanto, Evelyn, Mak, Tak W., Arsenian Henriksson, Marie, Wilhelm, Margareta T.
Format: Artigo
Langue:Inglês
Publié: National Academy of Sciences 2015
Sujets:
Biological Sciences
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4291634/
https://ncbi.nlm.nih.gov/pubmed/25535357
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1421697112
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