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A novel mutation in the N-terminal domain of Drosophila BubR1 affects the spindle assembly checkpoint function of BubR1

The spindle assembly checkpoint (SAC) is a surveillance mechanism that ensures accurate segregation of chromosomes into two daughter cells. BubR1, a key component of the SAC, also plays a role in the mitotic timing since depletion of BubR1 leads to accelerated mitosis. We previously found that mutat...

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Bibliografische gegevens
Gepubliceerd in:Biol Open
Hoofdauteurs: Duranteau, Marie, Montagne, Jean-Jacques, Rahmani, Zohra
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: The Company of Biologists Ltd 2016
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5155540/
https://ncbi.nlm.nih.gov/pubmed/27742609
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/bio.021196
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