A molecular basis for the differential roles of Bub1 and BubR1 in the spindle assembly checkpoint

The spindle assembly checkpoint (SAC) monitors and promotes kinetochore–microtubule attachment during mitosis. Bub1 and BubR1, SAC components, originated from duplication of an ancestor gene. Subsequent sub-functionalization established subordination: Bub1, recruited first to kinetochores, promotes...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:eLife
Päätekijät: Overlack, Katharina, Primorac, Ivana, Vleugel, Mathijs, Krenn, Veronica, Maffini, Stefano, Hoffmann, Ingrid, Kops, Geert J P L, Musacchio, Andrea
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: eLife Sciences Publications, Ltd 2015
Aiheet:
Biochemistry
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4337726/
https://ncbi.nlm.nih.gov/pubmed/25611342
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.05269
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