BubR1 Promotes Bub3-Dependent APC/C Inhibition during Spindle Assembly Checkpoint Signaling

The spindle assembly checkpoint (SAC) prevents premature sister chromatid separation during mitosis. Phosphorylation of unattached kinetochores by the Mps1 kinase promotes recruitment of SAC machinery that catalyzes assembly of the SAC effector mitotic checkpoint complex (MCC). The SAC protein Bub3...

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Publicado no:Curr Biol
Main Authors: Overlack, Katharina, Bange, Tanja, Weissmann, Florian, Faesen, Alex C., Maffini, Stefano, Primorac, Ivana, Müller, Franziska, Peters, Jan-Michael, Musacchio, Andrea
Formato: Artigo
Idioma:Inglês
Publicado em: Cell Press 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5640511/
https://ncbi.nlm.nih.gov/pubmed/28943088
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cub.2017.08.033
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