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BubR1 Promotes Bub3-Dependent APC/C Inhibition during Spindle Assembly Checkpoint Signaling

The spindle assembly checkpoint (SAC) prevents premature sister chromatid separation during mitosis. Phosphorylation of unattached kinetochores by the Mps1 kinase promotes recruitment of SAC machinery that catalyzes assembly of the SAC effector mitotic checkpoint complex (MCC). The SAC protein Bub3...

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Bibliografske podrobnosti
izdano v:Curr Biol
Main Authors: Overlack, Katharina, Bange, Tanja, Weissmann, Florian, Faesen, Alex C., Maffini, Stefano, Primorac, Ivana, Müller, Franziska, Peters, Jan-Michael, Musacchio, Andrea
Format: Artigo
Jezik:Inglês
Izdano: Cell Press 2017
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5640511/
https://ncbi.nlm.nih.gov/pubmed/28943088
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cub.2017.08.033
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