Drosophila Polo regulates the spindle assembly checkpoint through Mps1-dependent BubR1 phosphorylation

Maintenance of genomic stability during eukaryotic cell division relies on the spindle assembly checkpoint (SAC) that prevents mitotic exit until all chromosomes are properly attached to the spindle. Polo is a mitotic kinase proposed to be involved in SAC function, but its role has remained elusive....

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Main Authors: Conde, Carlos, Osswald, Mariana, Barbosa, João, Moutinho-Santos, Tatiana, Pinheiro, Diana, Guimarães, Sofia, Matos, Irina, Maiato, Helder, Sunkel, Claudio E
Formato: Artigo
Idioma:Inglês
Publicado: European Molecular Biology Organization 2013
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3680734/
https://ncbi.nlm.nih.gov/pubmed/23685359
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2013.109
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