Downregulation of Hepatic Acetylation of Drugs in Chronic Renal Failure

Drug metabolism can be affected by chronic renal failure (CRF). Although it is known that several drugs that are known to be acetylated accumulate in CRF, the effect of CRF on N-acetyltransferase (NAT), the enzyme responsible for this acetylation, is unknown. Herein is reported that protein and gene...

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Detaylı Bibliyografya
Asıl Yazarlar: Simard, Emilie, Naud, Judith, Michaud, Josée, Leblond, Francois A., Bonnardeaux, Alain, Guillemette, Chantal, Sim, Edith, Pichette, Vincent
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society of Nephrology 2008
Konular:
Basic Research
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2440299/
https://ncbi.nlm.nih.gov/pubmed/18417721
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2007090974
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