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Downregulation of Hepatic Acetylation of Drugs in Chronic Renal Failure
Drug metabolism can be affected by chronic renal failure (CRF). Although it is known that several drugs that are known to be acetylated accumulate in CRF, the effect of CRF on N-acetyltransferase (NAT), the enzyme responsible for this acetylation, is unknown. Herein is reported that protein and gene...
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| Hlavní autoři: | , , , , , , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
American Society of Nephrology
2008
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2440299/ https://ncbi.nlm.nih.gov/pubmed/18417721 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2007090974 |
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