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Effects of serum from patients with chronic renal failure on rat hepatic cytochrome P450

1. In humans, chronic renal failure (CRF) is associated with decreased hepatic drug metabolism, particularly that mediated by the cytochrome P450 (P450). The mechanisms remain poorly understood. The present study aimed to investigate the effects of the serum of patients with CRF on liver P450, and t...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Michaud, Josée, Dubé, Pierre, Naud, Judith, Leblond, Francois A, Desbiens, Karine, Bonnardeaux, Alain, Pichette, Vincent
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2005
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1576090/
https://ncbi.nlm.nih.gov/pubmed/15700027
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0706138
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