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Downregulation of Hepatic Acetylation of Drugs in Chronic Renal Failure

Drug metabolism can be affected by chronic renal failure (CRF). Although it is known that several drugs that are known to be acetylated accumulate in CRF, the effect of CRF on N-acetyltransferase (NAT), the enzyme responsible for this acetylation, is unknown. Herein is reported that protein and gene...

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Bibliografske podrobnosti
Main Authors: Simard, Emilie, Naud, Judith, Michaud, Josée, Leblond, Francois A., Bonnardeaux, Alain, Guillemette, Chantal, Sim, Edith, Pichette, Vincent
Format: Artigo
Jezik:Inglês
Izdano: American Society of Nephrology 2008
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2440299/
https://ncbi.nlm.nih.gov/pubmed/18417721
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2007090974
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