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Structure and transcriptional regulation of the Nat2 gene encoding for the drug-metabolizing enzyme arylamine N-acetyltransferase type 2 in mice.

Arylamine N-acetyltransferases (NATs) are polymorphic enzymes, well-known for their role in the metabolism of drugs and carcinogens. Mice have three NAT isoenzymes, of which NAT2 is postulated to be involved in endogenous, as well as xenobiotic, metabolism. To understand expression of the murine Nat...

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Autori principali: Boukouvala, Sotiria, Price, Naomi, Plant, Kathryn E, Sim, Edith
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2003
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1223723/
https://ncbi.nlm.nih.gov/pubmed/12904181
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20030812
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