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NAT gene polymorphisms and susceptibility to Alzheimer's disease: identification of a novel NAT1 allelic variant

BACKGROUND: Alzheimer's disease is multifactorial, having environmental, toxicological and genetic risk factors. Impaired folate and homocysteine metabolism has been hypothesised to increase risk. In addition to its xenobiotic-metabolising capacity, human arylamine N-acetyltransferase type-1 (N...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Johnson, Nichola, Bell, Peter, Jonovska, Vesna, Budge, Marc, Sim, Edith
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2004
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC395831/
https://ncbi.nlm.nih.gov/pubmed/15142281
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2350-5-6
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