Development of homogeneous luminescence assays for histone demethylase catalysis and binding

Por Kawamura, Akane, Tumber, Anthony, Rose, Nathan R., King, Oliver N. F., Daniel, Michelle, Oppermann, Udo, Heightman, Tom D., Schofield, Christopher
Publicado no Anal Biochem (2010)

Large-Scale Structural Analysis of the Classical Human Protein Tyrosine Phosphatome

Por Barr, Alastair J., Ugochukwu, Emilie, Lee, Wen Hwa, King, Oliver N.F., Filippakopoulos, Panagis, Alfano, Ivan, Savitsky, Pavel, Burgess-Brown, Nicola A., Müller, Susanne, Knapp, Stefan
Publicado em 2009

Inhibition of Histone Demethylases by 4-Carboxy-2,2′-Bipyridyl Compounds

Por Chang, Kai-Hsuan, King, Oliver N.F., Tumber, Anthony, Woon, Esther C.Y., Heightman, Tom D., McDonough, Michael A., Schofield, Christopher J., Rose, Nathan R.
Publicado no ChemMedChem (2011)

Selective Inhibitors of the JMJD2 Histone Demethylases: Combined Nondenaturing Mass Spectrometric Screening and Crystallographic Approaches

Por Rose, Nathan R., Woon, Esther C. Y., Kingham, Guy L., King, Oliver N. F., Mecinović, Jasmin, Clifton, Ian J., Ng, Stanley S., Talib-Hardy, Jobina, Oppermann, Udo, McDonough, Michael A., Schofield, Christopher J.
Publicado em 2010

Quantitative High-Throughput Screening Identifies 8-Hydroxyquinolines as Cell-Active Histone Demethylase Inhibitors

Por King, Oliver N. F., Li, Xuan Shirley, Sakurai, Masaaki, Kawamura, Akane, Rose, Nathan R., Ng, Stanley S., Quinn, Amy M., Rai, Ganesha, Mott, Bryan T., Beswick, Paul, Klose, Robert J., Oppermann, Udo, Jadhav, Ajit, Heightman, Tom D., Maloney, David J., Schofield, Christopher J., Simeonov, Anton
Publicado em 2010

Highly selective inhibition of histone demethylases by de novo macrocyclic peptides

Por Kawamura, Akane, Münzel, Martin, Kojima, Tatsuya, Yapp, Clarence, Bhushan, Bhaskar, Goto, Yuki, Tumber, Anthony, Katoh, Takayuki, King, Oliver N. F., Passioura, Toby, Walport, Louise J., Hatch, Stephanie B., Madden, Sarah, Müller, Susanne, Brennan, Paul E., Chowdhury, Rasheduzzaman, Hopkinson, Richard J., Suga, Hiroaki, Schofield, Christopher J.
Publicado no Nat Commun (2017)

The Plant Growth Regulator Daminozide is a Selective Inhibitor of the Human KDM2/7 Histone Demethylases

Por Rose, Nathan R., Woon, Esther C.Y., Tumber, Anthony, Walport, Louise J., Chowdhury, Rasheduzzaman, Li, Xuan Shirley, King, Oliver N.F., Lejeune, Clarisse, Ng, Stanley S., Krojer, Tobias, Chan, Mun Chiang, Rydzik, Anna M., Hopkinson, Richard J., Che, Ka Hing, Daniel, Michelle, Strain-Damerell, Claire, Gileadi, Carina, Kochan, Grazyna, Leung, Ivanhoe K. H., Dunford, James, Yeoh, Kar Kheng, Ratcliffe, Peter J., Burgess-Brown, Nicola, von Delft, Frank, Muller, Susanne, Marsden, Brian, Brennan, Paul E., McDonough, Michael A., Oppermann, Udo, Klose, Robert J., Schofield, Christopher J., Kawamura, Akane
Publicado no J Med Chem (2012)

5-Carboxy-8-hydroxyquinoline is a Broad Spectrum 2-Oxoglutarate Oxygenase Inhibitor which Causes Iron Translocation

Por Hopkinson, Richard J., Tumber, Anthony, Yapp, Clarence, Chowdhury, Rasheduzzaman, Aik, WeiShen, Che, Ka Hing, Li, Xuan Shirley, Kristensen, Jan B. L., King, Oliver N. F., Chan, Mun Chiang, Yeoh, Kar Kheng, Choi, Hwanho, Walport, Louise J., Thinnes, Cyrille C., Bush, Jacob T., Lejeune, Clarisse, Rydzik, Anna M., Rose, Nathan R., Bagg, Eleanor A., McDonough, Michael A., Krojer, Tobias, Yue, Wyatt W., Ng, Stanley S., Olsen, Lars, Brennan, Paul E., Oppermann, Udo, Muller-Knapp, Susanne, Klose, Robert J., Ratcliffe, Peter J., Schofield, Christopher J., Kawamura, Akane
Publicado no Chem Sci (2013)