Structure of the human RECQ1 helicase reveals a putative strand-separation pin

Por Pike, Ashley C. W., Shrestha, Binesh, Popuri, Venkateswarlu, Burgess-Brown, Nicola, Muzzolini, Laura, Costantini, Silvia, Vindigni, Alessandro, Gileadi, Opher
Publicado em 2009

High-throughput production of human proteins for crystallization: The SGC experience

Por Savitsky, Pavel, Bray, James, Cooper, Christopher D.O., Marsden, Brian D., Mahajan, Pravin, Burgess-Brown, Nicola A., Gileadi, Opher
Publicado em 2010

Crystal structure of Porphyromonas gingivalis peptidylarginine deiminase: implications for autoimmunity in rheumatoid arthritis

Por Montgomery, Anna B, Kopec, Jolanta, Shrestha, Leela, Thezenas, Marie-Laetitia, Burgess-Brown, Nicola A, Fischer, Roman, Yue, Wyatt W, Venables, Patrick J
Publicado no Ann Rheum Dis (2016)

Large-Scale Structural Analysis of the Classical Human Protein Tyrosine Phosphatome

Por Barr, Alastair J., Ugochukwu, Emilie, Lee, Wen Hwa, King, Oliver N.F., Filippakopoulos, Panagis, Alfano, Ivan, Savitsky, Pavel, Burgess-Brown, Nicola A., Müller, Susanne, Knapp, Stefan
Publicado em 2009

High-performance liquid chromatography separation and intact mass analysis of detergent-solubilized integral membrane proteins

Por Berridge, Georgina, Chalk, Rod, D’Avanzo, Nazzareno, Dong, Liang, Doyle, Declan, Kim, Jung-In, Xia, Xiaobing, Burgess-Brown, Nicola, deRiso, Antonio, Carpenter, Elisabeth Paula, Gileadi, Opher
Publicado em 2011

Assessing cellular efficacy of bromodomain inhibitors using fluorescence recovery after photobleaching

Por Philpott, Martin, Rogers, Catherine M, Yapp, Clarence, Wells, Chris, Lambert, Jean-Philippe, Strain-Damerell, Claire, Burgess-Brown, Nicola A, Gingras, Anne-Claude, Knapp, Stefan, Müller, Susanne
Publicado em 2014

A prominent β-hairpin structure in the winged-helix domain of RECQ1 is required for DNA unwinding and oligomer formation

Por Lucic, Bojana, Zhang, Ying, King, Oliver, Mendoza-Maldonado, Ramiro, Berti, Matteo, Niesen, Frank H., Burgess-Brown, Nicola A., Pike, Ashley C. W., Cooper, Christopher D. O., Gileadi, Opher, Vindigni, Alessandro
Publicado em 2011

Expressing the human proteome for affinity proteomics: optimising expression of soluble protein domains and in vivo biotinylation

Por Keates, Tracy, Cooper, Christopher D.O., Savitsky, Pavel, Allerston, Charles K., Phillips, Claire, Hammarström, Martin, Daga, Neha, Berridge, Georgina, Mahajan, Pravin, Burgess-Brown, Nicola A., Müller, Susanne, Gräslund, Susanne, Gileadi, Opher
Publicado em 2012

Optimisation of a triazolopyridine based histone demethylase inhibitor yields a potent and selective KDM2A (FBXL11) inhibitor

Por England, Katherine S., Tumber, Anthony, Krojer, Tobias, Scozzafava, Giuseppe, Ng, Stanley S., Daniel, Michelle, Szykowska, Aleksandra, Che, KaHing, von Delft, Frank, Burgess-Brown, Nicola A., Kawamura, Akane, Schofield, Christopher J., Brennan, Paul E.
Publicado no Medchemcomm (2014)

Human SNM1A and XPF–ERCC1 collaborate to initiate DNA interstrand cross-link repair

Por Wang, Anderson T., Sengerová, Blanka, Cattell, Emma, Inagawa, Takabumi, Hartley, Janet M., Kiakos, Konstantinos, Burgess-Brown, Nicola A., Swift, Lonnie P., Enzlin, Jacqueline H., Schofield, Christopher J., Gileadi, Opher, Hartley, John A., McHugh, Peter J.
Publicado em 2011

Structural Insights into Functional Overlapping and Differentiation among Myosin V Motors

Por Nascimento, Andrey F. Z., Trindade, Daniel M., Tonoli, Celisa C. C., de Giuseppe, Priscila O., Assis, Leandro H. P., Honorato, Rodrigo V., de Oliveira, Paulo S. L., Mahajan, Pravin, Burgess-Brown, Nicola A., von Delft, Frank, Larson, Roy E., Murakami, Mario T.
Publicado em 2013

The PHD and Chromo Domains Regulate the ATPase Activity of the Human Chromatin Remodeler CHD4

Por Watson, Aleksandra A., Mahajan, Pravin, Mertens, Haydyn D.T., Deery, Michael J., Zhang, Wenchao, Pham, Peter, Du, Xiuxia, Bartke, Till, Zhang, Wei, Edlich, Christian, Berridge, Georgina, Chen, Yun, Burgess-Brown, Nicola A., Kouzarides, Tony, Wiechens, Nicola, Owen-Hughes, Tom, Svergun, Dmitri I., Gileadi, Opher, Laue, Ernest D.
Publicado em 2012

Structures of ABCB10, a human ATP-binding cassette transporter in apo- and nucleotide-bound states

Por Shintre, Chitra A., Pike, Ashley C. W., Li, Qiuhong, Kim, Jung-In, Barr, Alastair J., Goubin, Solenne, Shrestha, Leela, Yang, Jing, Berridge, Georgina, Ross, Jonathan, Stansfeld, Phillip J., Sansom, Mark S. P., Edwards, Aled M., Bountra, Chas, Marsden, Brian D., von Delft, Frank, Bullock, Alex N., Gileadi, Opher, Burgess-Brown, Nicola A., Carpenter, Elisabeth P.
Publicado em 2013

Potent and Selective KDM5 Inhibitor Stops Cellular Demethylation of H3K4me3 at Transcription Start Sites and Proliferation of MM1S Myeloma Cells

Por Tumber, Anthony, Nuzzi, Andrea, Hookway, Edward S., Hatch, Stephanie B., Velupillai, Srikannathasan, Johansson, Catrine, Kawamura, Akane, Savitsky, Pavel, Yapp, Clarence, Szykowska, Aleksandra, Wu, Na, Bountra, Chas, Strain-Damerell, Claire, Burgess-Brown, Nicola A., Ruda, Gian Filippo, Fedorov, Oleg, Munro, Shonagh, England, Katherine S., Nowak, Radoslaw P., Schofield, Christopher J., La Thangue, Nicholas B., Pawlyn, Charlotte, Davies, Faith, Morgan, Gareth, Athanasou, Nick, Müller, Susanne, Oppermann, Udo, Brennan, Paul E.
Publicado no Cell Chem Biol (2017)

The Plant Growth Regulator Daminozide is a Selective Inhibitor of the Human KDM2/7 Histone Demethylases

Por Rose, Nathan R., Woon, Esther C.Y., Tumber, Anthony, Walport, Louise J., Chowdhury, Rasheduzzaman, Li, Xuan Shirley, King, Oliver N.F., Lejeune, Clarisse, Ng, Stanley S., Krojer, Tobias, Chan, Mun Chiang, Rydzik, Anna M., Hopkinson, Richard J., Che, Ka Hing, Daniel, Michelle, Strain-Damerell, Claire, Gileadi, Carina, Kochan, Grazyna, Leung, Ivanhoe K. H., Dunford, James, Yeoh, Kar Kheng, Ratcliffe, Peter J., Burgess-Brown, Nicola, von Delft, Frank, Muller, Susanne, Marsden, Brian, Brennan, Paul E., McDonough, Michael A., Oppermann, Udo, Klose, Robert J., Schofield, Christopher J., Kawamura, Akane
Publicado no J Med Chem (2012)

8-Substituted Pyrido[3,4-d]pyrimidin-4(3H)-one Derivatives As Potent, Cell Permeable, KDM4 (JMJD2) and KDM5 (JARID1) Histone Lysine Demethylase Inhibitors

Por Bavetsias, Vassilios, Lanigan, Rachel M., Ruda, Gian Filippo, Atrash, Butrus, McLaughlin, Mark G., Tumber, Anthony, Mok, N. Yi, Le Bihan, Yann-Vaï, Dempster, Sally, Boxall, Katherine J., Jeganathan, Fiona, Hatch, Stephanie B., Savitsky, Pavel, Velupillai, Srikannathasan, Krojer, Tobias, England, Katherine S., Sejberg, Jimmy, Thai, Ching, Donovan, Adam, Pal, Akos, Scozzafava, Giuseppe, Bennett, James M., Kawamura, Akane, Johansson, Catrine, Szykowska, Aleksandra, Gileadi, Carina, Burgess-Brown, Nicola A., von Delft, Frank, Oppermann, Udo, Walters, Zoe, Shipley, Janet, Raynaud, Florence I., Westaway, Susan M., Prinjha, Rab K., Fedorov, Oleg, Burke, Rosemary, Schofield, Christopher J., Westwood, Isaac M., Bountra, Chas, Müller, Susanne, van Montfort, Rob L. M., Brennan, Paul E., Blagg, Julian
Publicado no J Med Chem (2016)