Crystal structure of Porphyromonas gingivalis peptidylarginine deiminase: implications for autoimmunity in rheumatoid arthritis

BACKGROUND: Periodontitis (PD) is a known risk factor for rheumatoid arthritis (RA) and there is increasing evidence that the link between the two diseases is due to citrullination by the unique bacterial peptidylarginine deiminase (PAD) enzyme expressed by periodontal pathogen Pophyromonas gingival...

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Detalhes bibliográficos
Publicado no:Ann Rheum Dis
Main Authors: Montgomery, Anna B, Kopec, Jolanta, Shrestha, Leela, Thezenas, Marie-Laetitia, Burgess-Brown, Nicola A, Fischer, Roman, Yue, Wyatt W, Venables, Patrick J
Formato: Artigo
Idioma:Inglês
Publicado em: BMJ Publishing Group 2016
Assuntos:
Basic and Translational Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4893104/
https://ncbi.nlm.nih.gov/pubmed/26209657
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/annrheumdis-2015-207656
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