Peptidylarginine deiminase from Porphyromonas gingivalis citrullinates human fibrinogen and α-enolase: Implications for autoimmunity in rheumatoid arthritis

OBJECTIVES: To investigate protein citrullination by the periodontal pathogen Porphyromonas gingivalis (P. gingivalis) as a potential mechanism for breaking tolerance to citrullinated proteins in rheumatoid arthritis (RA). METHODS: Expression of endogenous citrullinated proteins was analysed by immu...

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Autori principali: Wegner, Natalia, Wait, Robin, Sroka, Aneta, Eick, Sigrun, Nguyen, Ky-Anh, Lundberg, Karin, Kinloch, Andrew, Culshaw, Shauna, Potempa, Jan, Venables, Patrick J
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2010
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2941529/
https://ncbi.nlm.nih.gov/pubmed/20506214
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/art.27552
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