MCAT Mutations Cause Nuclear LHON-like Optic Neuropathy

af Gerber, Sylvie, Orssaud, Christophe, Kaplan, Josseline, Johansson, Catrine, Rozet, Jean-Michel
Udgivet i Genes (Basel) (2021)

A Parsimonious Mechanism of Sugar Dehydration by Human GDP-Mannose-4,6-dehydratase

af Pfeiffer, Martin, Johansson, Catrine, Krojer, Tobias, Kavanagh, Kathryn L, Oppermann, Udo, Nidetzky, Bernd
Udgivet i ACS Catal (2019)

Virtual Fragment Screening Identification of a Quinoline‐5,8‐dicarboxylic Acid Derivative as a Selective JMJD3 Inhibitor

af Giordano, Assunta, del Gaudio, Federica, Johansson, Catrine, Riccio, Raffaele, Oppermann, Udo, Di Micco, Simone
Udgivet i ChemMedChem (2018)

The roles of Jumonji-type oxygenases in human disease

af Johansson, Catrine, Tumber, Anthony, Che, KaHing, Cain, Peter, Nowak, Radoslaw, Gileadi, Carina, Oppermann, Udo
Udgivet i Epigenomics (2014)

The Reducing Activity of Glutaredoxin 3 Towards Cytoplasmic Substrate Proteins is Restricted by Methionine 43

af Porat, Amir, Lillig, Christopher Horst, Johansson, Catrine, Fernandes, Aristi Potamitou, Nilsson, Lennart, Holmgren, Arne, Beckwith, Jon
Udgivet 2007

Human UTY(KDM6C) Is a Male-specific N(ϵ)-Methyl Lysyl Demethylase

af Walport, Louise J., Hopkinson, Richard J., Vollmar, Melanie, Madden, Sarah K., Gileadi, Carina, Oppermann, Udo, Schofield, Christopher J., Johansson, Catrine
Udgivet 2014

Identification of the 2-Benzoxazol-2-yl-phenol Scaffold as New Hit for JMJD3 Inhibition

af Giordano, Assunta, Forte, Giovanni, Terracciano, Stefania, Russo, Alessandra, Sala, Marina, Scala, Maria C., Johansson, Catrine, Oppermann, Udo, Riccio, Raffaele, Bruno, Ines, Di Micco, Simone
Udgivet i ACS Med Chem Lett (2019)

Lysine methylation-dependent binding of 53BP1 to the pRb tumor suppressor

af Carr, Simon M., Munro, Shonagh, Zalmas, Lykourgos-Panagiotis, Fedorov, Oleg, Johansson, Catrine, Krojer, Tobias, Sagum, Cari A., Bedford, Mark T., Oppermann, Udo, La Thangue, Nicholas B.
Udgivet 2014

Studies on the Interaction of the Histone Demethylase KDM5B with Tricarboxylic Acid Cycle Intermediates

af Tarhonskaya, Hanna, Nowak, Radosław P., Johansson, Catrine, Szykowska, Aleksandra, Tumber, Anthony, Hancock, Rebecca L., Lang, Pauline, Flashman, Emily, Oppermann, Udo, Schofield, Christopher J., Kawamura, Akane
Udgivet i J Mol Biol (2017)

Inhibition of histone H3K27 demethylases inactivates brachyury (TBXT) and promotes chordoma cell death

af Cottone, Lucia, Cribbs, Adam P, Khandelwal, Garima, Wells, Graham, Ligammari, Lorena, Philpott, Martin, Tumber, Anthony, Lombard, Patrick, Hookway, Edward S, Szommer, Tamas, Johansson, Catrine, Brennan, Paul E, Pillay, Nischalan, Jenner, Richard G, Oppermann, Udo, Flanagan, Adrienne M
Udgivet i Cancer Res (2020)

Investigating D-Lysine Stereochemistry for Epigenetic Methylation, Demethylation and Recognition

af Belle, Roman, Al Temimi, Abbas H. K., Kumar, Kiran, Pieters, Bas J. G. E., Tumber, Anthony, Dunford, James E., Johansson, Catrine, Oppermann, Udo, Brown, Tom, Schofield, Christopher J., Hopkinson, Richard J., Paton, Robert S., Kawamura, Akane, Mecinović, Jasmin
Udgivet i Chem Commun (Camb) (2017)

Discovery of Orally Bioavailable, Quinoline-Based Aldehyde Dehydrogenase 1A1 (ALDH1A1) Inhibitors with Potent Cellular Activity

af Yang, Shyh-Ming, Martinez, Natalia J., Yasgar, Adam, Danchik, Carina, Johansson, Catrine, Wang, Yuhong, Baljinnyam, Bolormaa, Wang, Amy Q., Xu, Xin, Shah, Pranav, Cheff, Dorian, Wang, Xinran S., Roth, Jacob, Lal-Nag, Madhu, Dunford, James E., Oppermann, Udo, Vasiliou, Vasilis, Simeonov, Anton, Jadhav, Ajit, Maloney, David J.
Udgivet i J Med Chem (2018)

Potent and Selective KDM5 Inhibitor Stops Cellular Demethylation of H3K4me3 at Transcription Start Sites and Proliferation of MM1S Myeloma Cells

af Tumber, Anthony, Nuzzi, Andrea, Hookway, Edward S., Hatch, Stephanie B., Velupillai, Srikannathasan, Johansson, Catrine, Kawamura, Akane, Savitsky, Pavel, Yapp, Clarence, Szykowska, Aleksandra, Wu, Na, Bountra, Chas, Strain-Damerell, Claire, Burgess-Brown, Nicola A., Ruda, Gian Filippo, Fedorov, Oleg, Munro, Shonagh, England, Katherine S., Nowak, Radoslaw P., Schofield, Christopher J., La Thangue, Nicholas B., Pawlyn, Charlotte, Davies, Faith, Morgan, Gareth, Athanasou, Nick, Müller, Susanne, Oppermann, Udo, Brennan, Paul E.
Udgivet i Cell Chem Biol (2017)

Lysine Demethylase 5A Is Required for MYC-Driven Transcription in Multiple Myeloma

af Ohguchi, Hiroto, Park, Paul M.C., Wang, Tingjian, Gryder, Berkley E., Ogiya, Daisuke, Kurata, Keiji, Zhang, Xiaofeng, Li, Deyao, Pei, Chengkui, Masuda, Takeshi, Johansson, Catrine, Wimalasena, Virangika K., Kim, Yong, Hino, Shinjiro, Usuki, Shingo, Kawano, Yawara, Samur, Mehmet K., Tai, Yu-Tzu, Munshi, Nikhil C., Matsuoka, Masao, Ohtsuki, Sumio, Nakao, Mitsuyoshi, Minami, Takashi, Lauberth, Shannon, Khan, Javed, Oppermann, Udo, Durbin, Adam D., Anderson, Kenneth C., Hideshima, Teru, Qi, Jun
Udgivet i Blood Cancer Discov (2021)

8-Substituted Pyrido[3,4-d]pyrimidin-4(3H)-one Derivatives As Potent, Cell Permeable, KDM4 (JMJD2) and KDM5 (JARID1) Histone Lysine Demethylase Inhibitors

af Bavetsias, Vassilios, Lanigan, Rachel M., Ruda, Gian Filippo, Atrash, Butrus, McLaughlin, Mark G., Tumber, Anthony, Mok, N. Yi, Le Bihan, Yann-Vaï, Dempster, Sally, Boxall, Katherine J., Jeganathan, Fiona, Hatch, Stephanie B., Savitsky, Pavel, Velupillai, Srikannathasan, Krojer, Tobias, England, Katherine S., Sejberg, Jimmy, Thai, Ching, Donovan, Adam, Pal, Akos, Scozzafava, Giuseppe, Bennett, James M., Kawamura, Akane, Johansson, Catrine, Szykowska, Aleksandra, Gileadi, Carina, Burgess-Brown, Nicola A., von Delft, Frank, Oppermann, Udo, Walters, Zoe, Shipley, Janet, Raynaud, Florence I., Westaway, Susan M., Prinjha, Rab K., Fedorov, Oleg, Burke, Rosemary, Schofield, Christopher J., Westwood, Isaac M., Bountra, Chas, Müller, Susanne, van Montfort, Rob L. M., Brennan, Paul E., Blagg, Julian
Udgivet i J Med Chem (2016)

The Prolyl-tRNA Synthetase Inhibitor Halofuginone Inhibits SARS-CoV-2 Infection

af Sandoval, Daniel R., Clausen, Thomas Mandel, Nora, Chelsea, Cribbs, Adam P., Denardo, Andrea, Clark, Alex E., Garretson, Aaron F., Coker, Joanna K.C., Narayanan, Anoop, Majowicz, Sydney A., Philpott, Martin, Johansson, Catrine, Dunford, James E., Spliid, Charlotte B., Golden, Gregory J., Payne, N. Connor, Tye, Mark A., Nowell, Cameron J., Griffis, Eric R., Piermatteo, Ann, Grunddal, Kaare V., Alle, Thibault, Magida, Jason A., Hauser, Blake M., Feldman, Jared, Caradonna, Timothy M., Pu, Yuan, Yin, Xin, McVicar, Rachael N., Kwong, Elizabeth M., Weiss, Ryan J., Downes, Michael, Tsimikas, Sotirios, Smidt, Aaron G., Ballatore, Carlo, Zengler, Karsten, Evans, Ron M., Chanda, Sumit K., Croker, Ben A., Leibel, Sandra L., Jose, Joyce, Mazitschek, Ralph, Oppermann, Udo, Esko, Jeffrey D., Carlin, Aaron F., Gordts, Philip L.S.M.
Udgivet i bioRxiv (2021)