Human UTY(KDM6C) Is a Male-specific N(ϵ)-Methyl Lysyl Demethylase

The Jumonji C lysine demethylases (KDMs) are 2-oxoglutarate- and Fe(II)-dependent oxygenases. KDM6A (UTX) and KDM6B (JMJD3) are KDM6 subfamily members that catalyze demethylation of N(ϵ)-methylated histone 3 lysine 27 (H3K27), a mark important for transcriptional repression. Despite reports stating...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Autori principali: Walport, Louise J., Hopkinson, Richard J., Vollmar, Melanie, Madden, Sarah K., Gileadi, Carina, Oppermann, Udo, Schofield, Christopher J., Johansson, Catrine
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Biochemistry and Molecular Biology 2014
Soggetti:
Enzymology
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4140284/
https://ncbi.nlm.nih.gov/pubmed/24798337
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.555052
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !

Documenti analoghi